Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Molecular and Cellular Insights to Ion Channel Biology
Annotation Contains fresh perspectives and up-to-date view points from international experts Illustrates the diverse array of techniques applied to ion channel research Represents a valuable resource to both the beginner and expert researcher, with over 2500 references and more than 100 figures and tables.
The Neuron
Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.
Neuromodulation
"Traditional neuroscience texts have stressed the output of neurons, how they turn postsynaptic targets on or off, cause muscles to twitch or convert photons into electrical pulses. Neuromodulation alters that emphasis to examine how the responses of nerve cells can be modified. Because a neuron's performance can be modulated, brains of all animals exhibit the amazing capacity to learn. Presenting the best-studied examples, Kaczmarek and Levitan provide the first detailed review of those potassium and calcium channels whose functions are modulated through receptor-mediated second messenger mechanisms and that are thought to underlie many important kinds of neuronal plasticity. This book, which covers up-to-date biophysical work in both vertebrate and invertebrate neurons, will be greatly appreciated by the readership the authors wish to reach: neurophysiological biochemists and biochemical neurophysiologists interested in understanding how behavior results from the action of nerve cells."--James H. Schwartz, M.D., Ph.D., Columbia University College of Physicians and Surgeons
Auditory Development and Plasticity
This volume presents a set of essays that discuss the development and plasticity of the vertebrate auditory system. The topic is one that has been considered before in the Springer Handbook of Auditory Research (volume 9 in 1998, and volume 23 in 2004) but the field has grown substantially and it is appropriate to bring previous material up to date to reflect the wealth of new data and to raise some entirely new topics. At the same time, this volume is also unique in that it is the outgrowth of a symposium honoring two-time SHAR co-editor Professor Edwin W Rubel on his retirement. The focus of this volume, though, is an integrated set of papers that reflect the immense contributions that Dr....
Neural and Synaptic Defects in Autism Spectrum Disorders
Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of potential therapeutic targets for autism and other cognitive disorders. Our Research Topic which constitutes this e-book documents the recent development and ideas in the study of pathogenesis and treatment of ASDs, with an emphasis on syndromic disorders such as fragile X and Rett syndromes. In addition, model systems and methodological approaches with translational relevance to autism are covered herein. We hope that the Research Topic will enhance the global knowledge base in the autism research community and foster new research directions in autism related biology.
Structure, Function, and Modulation of Neuronal Voltage-Gated Ion Channels
This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the channel genome, the physiological bases of targeting ion channels in disease, the unique technologies developed for ion channel drug discovery, and the increasingly important role of ion channel screening in cardiac risk assessment. It provides an important reference for research scientists and drug discovery companies.
Drug Development in Psychiatry
The book reviews clinical trial methodology as it pertains to drug development in psychiatry. The reader will understand the process of drug development in psychiatry from discovery through marketing with the help of clinically relevant examples. The reader will appreciate the history of drug development in psychiatry dating back to the era of serendipitous discovery and culminating in an era of new and highly focused targets. Readers will understand how drug development in psychiatry has changed and adapted with the discovery of novel mechanism of action drugs. Novel drugs and disease targets have changed the way developers and regulatory agencies think about clinical trial methodology. The...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
The Oxford Handbook of the Auditory Brainstem
The Oxford Handbook of The Auditory Brainstem provides an introduction as well as an in-depth reference to the organization and function of ascending and descending auditory pathways in the mammalian brainstem. Individual chapters are organized along the auditory pathway beginning with the cochlea and ending with the auditory midbrain. Each chapter provides an introduction to the respective area, and summarizes our current knowledge before discussing disputes and challenges the field currently faces. A major emphasis throughout this book is on the numerous forms of plasticity that are increasingly observed in many areas of the auditory brainstem. Several chapters focus on neuronal modulation...
The Oxford Handbook of Neuronal Ion Channels
Neurons are excitable cells. They use ions and electrical signaling to talk to each to other and when they talk to each other, neurons control behavior. The Oxford Handbook of Neuronal Ion Channels is an accessible reference describing the nature and properties of ion channels in neurons. The book explains how ion channels open and close, how they can be selective for specific ions, and how they give rise to action potentials. Included are in-depth chapters discussing specific classes of ion channels: potassium channels, sodium channels, neurotransmitter-gated ion channels and other specialized channels. Throughout the handbook, important insight is provided on the contribution ion channels make to neuronal excitability and to synaptic transmission. The handbook goes further to discuss channelopathies, a group of human diseases such as epilepsy, pain and migraines that can be caused by ion channel dysfunction. For neuroscientists, biophysicists and neuropharmacologists, this handbook is a valuable reference of ion channel biology and function.
