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Neural-Immune Interactions in Brain Function and Alcohol Related Disorders
  • Language: en
  • Pages: 587

Neural-Immune Interactions in Brain Function and Alcohol Related Disorders

Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in neuroinflammatory response, have been implicated in the regulation of neuronal function and plasticity. Thus, neural-immune interactions provide a new frame work for understanding the role of the neuroimmune system in normal brain function, neurodevelopment, and a variety of neurological disorders. These advances have a far reaching impact on many areas of neuroscience, including alcohol research. Studies using human alcoholic brains, gene knockout mice, and gene expression profiling have establis...

Improving the Utility and Translation of Animal Models for Nervous System Disorders
  • Language: en
  • Pages: 111

Improving the Utility and Translation of Animal Models for Nervous System Disorders

Nervous system diseases and disorders are highly prevalent and substantially contribute to the overall disease burden. Despite significant information provided by the use of animal models in the understanding of the biology of nervous system disorders and the development of therapeutics; limitations have also been identified. Treatment options that are high in efficacy and low in side effects are still lacking for many diseases and, in some cases are nonexistent. A particular problem in drug development is the high rate of attrition in Phase II and III clinical trials. Why do many therapeutics show promise in preclinical animal models but then fail to elicit predicted effects when tested in ...

Scientific Directory and Annual Bibliography
  • Language: en
  • Pages: 428

Scientific Directory and Annual Bibliography

  • Type: Book
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  • Published: Unknown
  • -
  • Publisher: Unknown

None

Pioneers in Neuroendocrinology
  • Language: en
  • Pages: 323

Pioneers in Neuroendocrinology

In the middle and late 1960s, when it was clear that neuroendocrinology was established as a discipline in its own right, it occurred to us that auto biographical accounts of the pioneer work in this field by the major par ticipants would provide a highly interesting and informative account of his tory in the making. With the death of G. W. Harris in late 1971, and the loss thereby of an outstanding pioneer and personality in neuroendocri nology, it appeared to us to be even more urgent to undertake such a ven ture and collect as many stories as possible. The three of us agreed that initially we would limit our invitations to the senior investigators whose re search careers lay mostly behind...

The Dundee directory
  • Language: en
  • Pages: 193

The Dundee directory

Containing, list of names - public bodies, charitable institutions - public offices, shipping.

Research Awards Index
  • Language: en
  • Pages: 676

Research Awards Index

  • Type: Book
  • -
  • Published: 1980
  • -
  • Publisher: Unknown

None

Hdbk PHARMCOLOGIC Meethodology for Stdy of Neuroendocrine Sy
  • Language: en
  • Pages: 458

Hdbk PHARMCOLOGIC Meethodology for Stdy of Neuroendocrine Sy

  • Type: Book
  • -
  • Published: 1985-05
  • -
  • Publisher: Springer

None

Research Awards Index
  • Language: en
  • Pages: 686

Research Awards Index

  • Type: Book
  • -
  • Published: 1979
  • -
  • Publisher: Unknown

None

Federation Proceedings
  • Language: en
  • Pages: 1236

Federation Proceedings

  • Type: Book
  • -
  • Published: 1983
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  • Publisher: Unknown

Vols. for 1942- include proceedings of the American Physiological Society.

Neuroactive Drugs in Endocrinology
  • Language: en
  • Pages: 432

Neuroactive Drugs in Endocrinology

In Brattleboro, Vermont, Lieutenant Joe Gunther juggles several cases, all of which turn out to be connected. There is the murder of a girl runaway, the disappearance of a local activist, the death of a homeless man, and the strangling of a woman due to die anyway.