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The ultimate goal of functional brain imaging is to provide optimal estimates of the neural signals flowing through the long-range and local pathways mediating all behavioral performance and conscious experience. In functional MRI (Magnetic Resonance Imaging), despite its impressive spatial resolution, this goal has been somewhat undermined by the fact that the fMRI response is essentially a blood-oxygenation level dependent (BOLD) signal that only indirectly reflects the nearby neural activity. The vast majority of fMRI studies restrict themselves to describing the details of these BOLD signals and deriving non-quantitative inferences about their implications for the underlying neural activ...
The brain is the most complex computational device we know, consisting of highly interacting and redundant networks of areas, supporting specific brain functions. The rules by which these areas organize themselves to perform specific computations have only now started to be uncovered. Advances in non-invasive neuroimaging technologies have revolutionized our understanding of the functional anatomy of cortical circuits in health and disease states, which is the focus of this book. The first section of this book focuses on methodological issues, such as combining functional MRI technology with other brain imaging modalities. The second section examines the application of brain neuroimaging to understand cognitive, visual, auditory, motor and decision-making networks, as well as neurological diseases. The use of non-invasive neuroimaging technologies will continue to stimulate an exponential growth in understanding basic brain processes, largely as a result of sustained advances in neuroimaging methods and applications.
Computer Vision is the first book to take a full approach to the challenging issue of veridical 3D object representation. It introduces mathematical and conceptual advances that offer an unprecedented framework for analyzing the complex scene structure of the world. Leading theorists cover full 3D scene reconstruction, instead of the simplistic 2D planar algorithms employed in the past. They explore cutting-edge research on computational algorithms for scene analysis and present an integrated, complementary treatment of neural, behavioral, mathematical, and computational approaches. The text includes numerous graphics of complex processes, with many in color.
This book provides comprehensive and up-to-date insights into emerging research trends on neuroplasticity with current or future treatments for neurodevelopment and neurodegenerative diseases. The authors discuss structural and functional changes associated with cortical remapping, sensory substitution, synaptic and non-synaptic compensatory plasticity due to brain damage, brain training, chronic pain, meditation, music, exercise and related states. Key features include pathogenesis, and existing and new therapies together with a pharmacological and non-pharmacological approach in clinical treatment and management. The authors are established experts that contributed significantly to a better understanding of the etiology of neuroplasticity. This book is recommended to healthcare providers, clinical scientists, students and patients.
Could we understand, in biological terms, the unique and fantastic capabilities of the human brain to both create and enjoy art? In the past decade neuroscience has made a huge leap in developing experimental techniques as well as theoretical frameworks for studying emergent properties following the activity of large neuronal networks. These methods, including MEG, fMRI, sophisticated data analysis approaches and behavioral methods, are increasingly being used in many labs worldwide, with the goal to explore brain mechanisms corresponding to the artistic experience. The 37 articles composing this unique Frontiers Research Topic bring together experimental and theoretical research, linking st...
Our ability to be conscious of the world around us is often discussed as one of the most amazing yet enigmatic processes under scientific investigation today. However, our ability to imagine the world around us in the absence of stimulation from that world is perhaps even more amazing. This capacity to experience objects or scenarios through imagination, that do not necessarily exist in the world, is perhaps one of the fundamental abilities that allows us successfully to think about, plan, run a dress rehearsal of future events, re-analyze past events and even simulate or fantasize abstract events that may never happen. Empirical research into mental imagery has seen a recent surge, due part...
The neural correlates of hand preference are still debatable, and the very few studies on the mechanisms of enforced change of handedness from left to right are all restricted to early childhood. We were able to address the question of retraining handedness in late adulthood for the first time, well outside the accepted critical period for brain plasticity, through a unique training utilizing the complex motor task of blind memory-guided drawing, in a totally blind, congenitally left-handed man. Ten hours of this Cognitive-Kinesthetic Drawing Training, which the author initially developed to drive neuroplasticity in blindness rehabilitation, was sufficient to generate a profound switch in the cortical lateralization of motor control. This study provides new insights into the neuroplasticity of motor control architecture. The results are of high relevance to the long-standing debate about the sources of hemispheric asymmetry. The unprecedented effect on handedness of the rapid Cognitive-Kinesthetic Drawing Training implies a powerful potential of this training for further rehabilitation domains, such as the rehabilitation of stroke or trauma affecting hand control.
Proceedings of a national conference on the management of functional visual deficits in mild traumatic brain injury (mTBI), held at the Smith-Kettlewell Eye Research Institute, in San Francisco, California on March 4-5, 2011. This volume was edited by Christopher W. Tyler. The event was organized by Arthur Jampolsky, John Brabyn, William Good, Christopher Tyler, Glenn Cockerham, Gregory Goodrich, Ronald Schuchard and Bebe St. John.