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Autoritratto dell'immondizia
«Leggendo queste pagine ci si rende conto di come la storia delle civiltà e quella dell'immondizia abbiano percorso un cammino parallelo: le civiltà sul piano alto, tra splendori e incensi, l'immondizia su quello basso, tra miasmi e focolai di infezioni. [...] La storia che ci racconta il libro parte da molto lontano [...] e via via narra come i micropredatori abbiano tormentato l'umanità attraverso i secoli (con infezioni, pestilenze ed epidemie di vario tipo) e come soltanto con la nascita della modernità sia stato possibile affrontare alla radice il problema: non solo grazie a nuove conoscenze scientifiche e mediche, ma attraverso una nuova organizzazione urbanistica e la creazione d...
Protein Kinase CK2
Protein kinases play a critical role in cellular processes that impact overall organismal health and function. Of the kinases that collectively make up the Human Kinome, CK2 has garnered special attention because of its significant role in the generation of the human phosphoproteome. The role CK2 plays in the development of cancer and other disease has also made it of significant interest for its potential role in future therapeutics. Protein Kinase CK2 comprehensively brings together the varied work being done on this critical enzyme. Protein Kinase CK2 is logically divided into three sections. The first section reviews key molecular and structural aspects of the enzyme. The second section ...
Protein Kinase CK2
Protein kinases play a critical role in cellular processes that impact overall organismal health and function. Of the kinases that collectively make up the Human Kinome, CK2 has garnered special attention because of its significant role in the generation of the human phosphoproteome. The role CK2 plays in the development of cancer and other disease has also made it of significant interest for its potential role in future therapeutics. Protein Kinase CK2 comprehensively brings together the varied work being done on this critical enzyme. Protein Kinase CK2 is logically divided into three sections. The first section reviews key molecular and structural aspects of the enzyme. The second section ...
An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2
This book is a printed edition of the Special Issue "An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2" that was published in Pharmaceuticals
Inhibitors of Protein Kinases and Protein Phosphates
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles.
Protein Kinase CK2 Cellular Function in Normal and Disease States
Protein kinase CK2 (formerly casein kinase II or 2) is known to play a critical role in the control of cell growth and cell death and is thus intimately involved in the development of cancer. More specifically, CK2 has been found to be elevated in all cancers examined. While CK2 levels are known to be high in proliferating normal cells, CK2 has also been found to be a potent suppressor of apoptosis and is a link to the cancer cell phenotype, which is characterized by deregulation of both cell proliferation and cell death. Indeed, it would appear that CK2 impacts many of the hallmarks of cancer and it has now gained considerable attention as a potential target for cancer therapy. Protein Kinase CK2 and Cellular Function in Normal and Disease States increases knowledge of the role of CK2 in the development of cellular dysfunction and emphasizes that this protein may serve as a target of drug development for improved cancer therapy. In addition, it is a handy tool that provides cancer researchers, graduate students, and all scientists involved in CK2 research with one main source for the latest advances in CK2 research.
Peptides and Protein Phosphorylation
This comprehensive volume focuses on the ways in which synthetic peptides have been exploited in order to expand our understanding of the molecular mechanisms involved in protein phosphorylation. It recognizes that virtually all physiological processes are regulated by protein phosphorylation. It discusses the use of synthetic peptides in studying the catalytic mechanism and regulation of protein kinases. It also includes the chemical synthesis of phosphorylated peptides and preparation of specific antisera. This incredible work has lead to the development of a new generation of peptide inhibitors with potencies of greater magnitude than those previously known. Everyone involved with biochemistry and molecular biology will find this one-of-a-kind resource fascinating and filled with useful information.
All I Need To Know I Learned From My College Bar
Adam Lorenzo owned a college bar while attending college at Syracuse University. No joke. Working and laughing with people from all over the world, he learned invaluable life lessons in that cathedral of knowledge known as a . . . college bar! Adam applied all of that knowledge when he changed career paths and graduated to accomplish his dream of becoming a television/movie writer . . . inspiring him to share that knowledge in his first book. A high-concept life-wisdom/humor book. It' s about thinking, not drinking. It features text and hilarious illustrations from Antonio Pinna. A perfect (graduation or any time) gift for students, parents, professors, teaching assistants, college sports fans, anyone who has ever stepped foot on a college campus, likes to laugh or just likes to watch other people laugh (albeit creepy).
