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Contemporary Physics
This proceedings volume reviews the current status of research in major frontline areas of physics. With contributions from leading physicists, the areas of research covered in the various papers include condensed matter physics, particle physics, quantum optics, quantum computing and laser physics, nanosciences, synchrotron radiation, relativity, astrophysics and cosmology, and plasma physics.
Macromolecular Crystallography
This volume is a collection of the contributions presented at the 42nd Erice Crystallographic Course whose main objective was to train the younger generation on advanced methods and techniques for examining structural and dynamic aspects of biological macromolecules. The papers review the techniques used to study protein assemblies and their dynamics, including X-ray diffraction and scattering, electron cryo-electron microscopy, electro nanospray mass spectrometry, NMR, protein docking and molecular dynamics. A key theme throughout the book is the dependence of modern structural science on multiple experimental and computational techniques, and it is the development of these techniques and their integration that will take us forward in the future.
Biochemistry
The most comprehensive textbook/reference ever to cover the chemical basis of life, the "Green Bible of Biochemistry" has been a well-respected contribution to the field for more than twenty years. The complex structures that make up cells are described in detail, along with the forces that hold them together, and the chemical reactions that allow for recognition, signaling and movement. There is ample information on the human body, its genome, and the action of muscles, eyes, and the brain. The complete set deals with the natural world, treating the metabolism of bacteria, toxins, antibiotics, specialized compounds made by plants, photosynthesis, luminescence of fireflies, among many other topics.* The most comprehensive biochemistry text reference available on the market* Organized into two volumes, comprising 32 chapters and containing the latest research in the field* Biological content is emphasized: for example, macromolecular structures and enzyme action are discussed
Allosteric Enzymes
This book compiles detailed information concerning a dozen of the best known allosteric enzymes, and so allows the comparison of their regulatory mechanisms and the confrontation of these mechanisms with the theoretical models. Stimulating and unexpected ideas emerge from these comparisons and emphasize the importance of developing various methods of investigation such as crystallography, X-ray solution scattering, and the study of fast movements in proteins and site-directed mutagenesis. This book is addressed to students and researchers interested in structure-function relationship in proteins, enzymology and metabolic regulation. It is also a basis for teaching.
The Biochemistry of Cell Signalling
The Biochemistry of Cell Signalling deals in depth with the principles of cell signalling, concentrating on structure and mechanism. It will serve as a reliable map through the maze of cell signalling pathways and help the reader understand how malfunctions in these pathways can lead to disease. The book is divided into four parts. Part 1 describes the machinery of signal transduction starting with the properties of signals, receptors (including receptor activation), regulators, and the molecules that link receptor and regulator. The design of signalling cascades is explained by describing central signalling pathways: the Ras-regulated MAPK and PI-3 pathways; the Rho/Rac/Cdc 42 pathway contr...
Bioluminescence And Chemiluminescence: Progress And Current Applications
The Proceedings of the 12th International Symposium on Bioluminescence (BL) and Chemiluminescence (CL) contains up-to-date information on the latest developments in BL and CL presented by scientists from around the world.Light-emitting reactions are now a vital component of many key technologies in research and in routine analytical laboratories — replacing radionuclides in many situations. This volume presents a compilation of the latest developments from key experts and leading-edge researchers in this area.
Bioluminescence & Chemiluminescence
The Proceedings of the 12th International Symposium on Bioluminescence (BL) and Chemiluminescence (CL) contains up-to-date information on the latest developments in BL and CL presented by scientists from around the world.Light-emitting reactions are now a vital component of many key technologies in research and in routine analytical laboratories OCo replacing radionuclides in many situations. This volume presents a compilation of the latest developments from key experts and leading-edge researchers in this area."
Biophysics and Synchrotron Radiation
This book the second volume in the "Springer Series in Biophysics" col lects together contributions to the conference on "Biophysics and Syn chrotron Radiation" held in July 86 at Frascati. This meeting addressed the advances on the structure of biological molecules obtained by using synchrotron radiation. In fact it was most timely to review the results of the research in biophysics which is rapidly developing at synchrotron radiation facilities. Moreover, there was interest to discuss the new perspectives opened up by the future high brilliance synchrotron radia tion sources. With the use of synchrotron radiation, x-ray spectroscopy of biological molecules is firmly established in the tech...
Molecular Biology of Assemblies and Machines
Molecular Biology of Assemblies and Machines provides a comprehensive narrative of the ways in which macromolecular structures assemble and how they interact with other complexes and organelles in the cell. Richly illustrated in full color, the text is written for advanced undergraduates, graduate students, and researchers in biochemistry, molecular biology, biophysics, cell biology, chemistry, structural biology, immunology, microbiology, and medicine.
Glycogen Phosphorylase B
This monograph describes the determination by X-ray methods and the structural analysis of one of the largest single polypeptide chain proteins, glycogen phosphorylase. It is shown that the large protein conforms to the rules deduced from smaller protein molecules and provides examples of almost every structural feature. The structure is analysed with special reference to the hydrogen bonding pattern of secondary structural elements, the distributions and interactions of the buried amino acids, the role of the water structure and the details of the subunit interface of the dimer. The results show some unusual secondary structural elements and environments for some side chain atoms. As methods for prediction of protein structures from amino acid sequences advance from assignments of secondary structural elements to predicted tertiary assemblies, knowledge of the preferred and exceptional detailed interactions of the amino acid side chains will need to be incorporated. Glycogen phosphorylase provides a wealth of examples of these interactions.This monograph is a useful reference on protein structure and function.
