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Behind the Red Door
The author of the “suspenseful, atmospheric, and completely riveting” (Megan Miranda, New York Times bestselling author) debut The Winter Sister returns with a darkly thrilling novel about a woman who comes to believe that she has a connection to a decades old kidnapping and now that the victim has gone missing again, begins a frantic search to learn what happened in the past. When Fern Douglas sees the news about Astrid Sullivan, a thirty-four-year-old missing woman from Maine, she is positive that she knows her. Fern’s husband is sure it’s because of Astrid’s famous kidnapping—and equally famous return—twenty years ago, but Fern has no memory of that, even though it happened ...
Glycogen Phosphorylase B
This monograph describes the determination by X-ray methods and the structural analysis of one of the largest single polypeptide chain proteins, glycogen phosphorylase. It is shown that the large protein conforms to the rules deduced from smaller protein molecules and provides examples of almost every structural feature. The structure is analysed with special reference to the hydrogen bonding pattern of secondary structural elements, the distributions and interactions of the buried amino acids, the role of the water structure and the details of the subunit interface of the dimer. The results show some unusual secondary structural elements and environments for some side chain atoms. As methods for prediction of protein structures from amino acid sequences advance from assignments of secondary structural elements to predicted tertiary assemblies, knowledge of the preferred and exceptional detailed interactions of the amino acid side chains will need to be incorporated. Glycogen phosphorylase provides a wealth of examples of these interactions.This monograph is a useful reference on protein structure and function.
Molecular Biology of Assemblies and Machines
Molecular Biology of Assemblies and Machines provides a comprehensive narrative of the ways in which macromolecular structures assemble and how they interact with other complexes and organelles in the cell. Richly illustrated in full color, the text is written for advanced undergraduates, graduate students, and researchers in biochemistry, molecular biology, biophysics, cell biology, chemistry, structural biology, immunology, microbiology, and medicine.
Children Of The Dust
A powerful post-nuclear holocaust novel described by the author as, 'my cry against the monstrous weapons men have made'. Everyone thought, when the alarm bell rang, that it was just another fire practice. But the first bombs had fallen on Hamburg and Leningrad, the headmaster said, and a full-scale nuclear attack was imminent . . . It's a real-life nightmare. Sarah and her family have to stay cooped up in the tightly-sealed kitchen for days on end, dreading the inevitable radioactive fall-out and the subsequent slow, torturous death, which seems almost preferable to surviving in a grey, dead world, choked by dust. But then, from out of the dust and the ruins and the desolation, comes new life, a new future, and a whole brave new world...
Post-translational Modifications of Proteins
Post-Translational Modifications of Proteins discusses several important topics of interest to researchers and students in protein chemistry and biochemistry, including the occurrence and function of hydroxylated residues and the three enzymes required for their formation; the damaging effects of reactions between sugars and proteins; ADP-riboosylation of proteins outside the nucleus; and Monod, Wyman, and Changeux's concerted model for allosteric control of enzyme activity exemplified by studies on glycogen phosphorylase. The application of Fast Atom Bombardment Mass Spectometry (FAB-MS) to studies on the structure and biosynthesis of various oligosaccharide moieties in protein is examined, and the understanding of the structural diversity and function of glycoprotein oligosaccharides is discussed in this volume.
A Nurse's Story
Moving, honest and inspiring – this is a nurse’s true story of life in a busy A&E department during the Covid-19 crisis. Working in A&E is a challenging job but nurse Louise Curtis loves it. She was newly qualified as an advanced clinical practitioner, responsible for life or death decisions about the patients she saw, when the unthinkable happened and the country was hit by the Covid-19 pandemic. The stress on the NHS was huge and for the first time in her life, the job was going to take a toll on Louise herself. In A Nurse’s Story she describes what happened next, as the trickle of Covid patients became a flood. And just as tragically, staff in A&E were faced with the effects of lockdown on society. They worried about their regulars, now missing, and saw an increase in domestic abuse victims and suicide attempts as loneliness hit people hard. By turns heartbreaking and heartwarming, this book shines a light on the compassion and dedication of hospital staff during such dark times. 'An important memoir that we all need to read right now.' – Closer
Leadership in Science and Technology: A Reference Handbook
Tackling 100 key topics and providing case studies in the area of science and technology leadership, this reference handbook is an essential resource for students in this area.
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