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Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances
This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provide critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.
Perfluoroalkyl Substances in the Environment
Per- and polyfluorinated alkyl substances (PFAS), often referred to as per- (and poly) fluorinated compounds (PFCs), have been used for years in many everyday3⁄4 and some lifesaving3⁄4 products. However, their use has been linked to adverse health effects in humans, a problem compounded by their persistence in the environment. This book discusses the various challenges of PFAS in our environment today, including their historical use as well as their chemical and toxicological properties. It also presents robust discussion of analytical challenges and special considerations in sampling. The work goes on to give practical recommendations for dealing with these compounds in today's dynamic ...
Developmental Endocrinology
Leading researchers comprehensively translate all the latest scientific information regarding endocrine physiology and development into an understanding of the clinical pathogenesis, diagnosis, and treatment of endocrine disease. Organized by endocrine system, each section of the book concisely describes the chronological development of the human organism, from the fetal/prenatal period through childhood, adolescence, and in some cases, into adulthood. The prenatal sections review recent discoveries concerning transcription factors, homeobox genes, and human molecular mutations-the basic processes governing prenatal development of the individual endocrine organs-and detail the pathophysiology, clinical characteristics, and treatment of pediatric endocrine disorders.
Natural Attenuation of Chlorinated Solvents, Petroleum Hydrocarbons, and Other Organic Compounds
Natural attenuation was first demonstrated at sites with hydrocarbon contamination, but recent studies at sites contaminated by chlorinated compounds have shown that this approach often has merit for these more challenging contamination problems. This volume covers natural attenuation in media ranging from deep aquifers to shallow soils, and for contaminants ranging from fuels to solvents to herbicides, and offers the reader a comprehensive overview of case studies that represent the state of the art in natural attenuation approaches to site remediation.
Environmental Endocrinology
From 11 to 15 July 1977 about 60 physiologists, endo crinologists, ecologists and other biologists from 14 countries convened at the University Montpellier for a symposium on Environmental Endocrinology. This meet ing was organized as a Satellite Symposium of the 27th International Congress of Physiological Sciences, Paris, 18-23 July 1977. This volume is a record of the com munications presented at the symposium. The objectives of the program were to examine the role of the endocrine system in a wide spectrum of adjustments and adaptations to changes in environmental conditions by various spe cies of animals, including man, and to promote an ex change of ideas among investigators who have a...
Dermal Exposure
"IPCS, International Programme on Chemical Safety."
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Organofluorine Chemistry
During the past fifteen years commercial interest in compounds containing carbon fluorine bonds has burgeoned beyond all expectations, mainly owing to business opportunities arising from work on biologically active fluoroorganics-particularly agrochemicals, the relentless search for new markets for fluoropolymers and fluoro carbon fluids, developments in the field of medical diagnostics, and the drive to find replacements for ozone-depleting CFCs and Halon fire-extinguishing agents. Judging the situation to warrant the publication of a comprehensive collection of up-to-date reviews dealing with commercial organofluorine compounds within a single volume of manageable size (and hence reasonabl...
Social Networks and Natural Resource Management
Social Network Analysis (SNA), a quantitative approach to the study of social relations, has recently emerged as a key tool for understanding the governance of natural resources. Bringing together contributions from a range of researchers in the field, this is the first book to fully explore the potential applications of SNA in the context of natural resource management. Topics covered include the role of SNA in stakeholder selection; improving fisheries management and conservation; the effect of social network ties on public satisfaction and agrarian communication networks. Numerous case studies link SNA concepts to the theories underlying natural resource governance, such as social learning, adaptive co-management and social movements theory. Reflecting on the challenges and opportunities associated with this evolving field, this is an ideal resource for students and researchers involved in many areas of natural resource management, environmental biology, sustainability science and sociology.
