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The co-discoverer of HIV and one of the world's preeminent virologists relates the Pasteur Institute's leading role in investigating the AIDS virus and the virus's devastating course throughout the world. Photos.
Based on a conference on Oxidative Stress and Redox Regulation, held at the Pasteur Institute, Paris, this work examines fundamental, chemical, biological and medical studies of free radicals on different targets and the consequences of their reactivity. It covers the chemistry and biochemistry of free radicals, free radicals as second messengers that group the activation of transcription factors and enzymes, the importance of the antioxidant system in cell metabolism regulation, and the role of free radicals and antioxidants in disease management. The editors of this work are three of the most respected pioneers in the field. Dr. Montagnier is credited as the discoverer of HIV.
In the early 1980s, doctors sounded the alarm. A mysterious new disease—acquired immunodeficiency syndrome, or AIDS—was spreading around the world. While many of the first AIDS patients were gay men, no one seemed to be immune from the deadly blood-borne disease. Researchers set to work to discover what was causing AIDS. They suspected a virus. Two teams of scientists—one in the United States and one in France—worked tirelessly to identify the virus and to develop a blood test to detect it. The news on April 23, 1984, that the U.S. team, led by Robert Gallo at the National Cancer Institute, had isolated the virus was a cause for celebration. But in Paris, France, Luc Montagnier and h...
A Pulitzer Prize-winning journalist describes the competition between scientists--including Robert Gallo of the National Cancer Institute--over credit for the discovery of the HIV virus in a study that offers a revealing look at how big scientific and research laboratories really work. Reprint. 20,000 first printing.
The author of The Eudaemonic Pie now reveals the inspiration, motivations, and aspirations of the world's greatest scientists. The scientists interviewed in this collection have changed the rules of the game--altered our perception of reality and the language used to describe it.
Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Approximately 15-20% of all cases of cancer around the world are caused by viruses. The establishment of a causal relationship between the presence of specific infective agents and certain types of human cancer represents a key step in the development of novel therapeutic and preventive strategies. In this book, Professor zur Hausen (Nobel Prize in Physiology/Medicine 2008) provides a thorough and comprehensive overview on carcinogenic infective agents -- viruses, bacteria, parasites and protozoons -- as well as their corresponding transforming capacities and mechanisms. The result is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer. The author was among the first scientists to reveal the cervical cancer-inducing mechanisms of human papilloma viruses and isolated HPV16 and HPV18, and, as early as 1976, published the hypothesis that wart viruses play a role in the development of this type of cancer.
Water is the most every day of substances. It pours from our taps and falls from the sky. We drink it, wash with it, and couldn't live without it. Yet, on closer examination it is also a very strange substance (it is one of only a very small number of molecules which expand when cooled). Look closer again and water reveals itself as a key to a scientific story on the biggest of canvases. Water is crucial to our survival - life depends on it - but it was also fundamental in the origins of life on Earth. The millions of gallons of water which make up our rivers, lakes and oceans, originated in outer space. How it arrived here and how those molecules of water were formed, is a story which takes...
Trailblazers in Science and Technology is a 10-volume set that profiles the lives and achievements of scientists whose work has had a major impact on a particular field. The scientist's accomplishments are discussed, including the "trailblazing" principles and personal struggles that complemented his or her work. Employing an array of primary sources-diaries, memoirs, letters, and contemporary news accounts-as well as secondary sources, the set depicts the human drama of scientific work, the challenge of research, and the exhilaration and rewards of discovery. Luc Montagnier recounts the life and career of the Nobel Prize-winning French virologist whose contributions to the understanding of ...
By drawing on the latest discoveries in virology, microbiology, and immunology, Mirko Grmek depicts the AIDS epidemic not as an isolated incident but as part of the long, but far from peaceful, coexistence of humans and viruses.
Traces the history of western medicine through the lives of its major contributors, profiling such well-known figures as Hippocrates and Louis Pasteur, as well as lesser-known scientists including Elle Metchnikoff and Samuel Hahnemann.