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Pharmacology
The history of pharmacology travels together to history of scientific method and the latest frontiers of pharmacology open a new world in the search of drugs. New technologies and continuing progress in the field of pharmacology has also changed radically the way of designing a new drug. In fact, modern drug discovery is based on deep knowledge of the disease and of both cellular and molecular mechanisms involved in its development. The purpose of this book was to give a new idea from the beginning of the pharmacology, starting from pharmacodynamic and reaching the new field of pharmacogenetic and ethnopharmacology.
Constipation
Constipation is common in both adults and children. Estimates would suggest a median prevalence of around 12-16% in the general population. While regarded as a minor nuisance in some cases, its consequences can be severe, with a substantial impact on quality of life. Secondary faecal soiling has a profound psychological effect at all ages. This book provides contributions from authors with a range of backgrounds which clarify the pathogenesis, diagnosis, and therapy of constipation for the general population and also for certain high risk groups.
Miniaturized Electrochemical Devices
Evidently, electrochemical sensing has revolutionized the electroanalytical detections in the world. Since the 19th century, a huge amount of growth has been visible on various fronts, such as biosensors, energy devices, semiconductor devices, communication, embedded systems, sensors etc. However, the major research gap lies in the fact that most of the reported literatures are bulk systems; hence there are limitations for practical applications. Research in these domains has been carried out by both academia and industry, whereby academics is the backbone whose intellectual outputs have been widely adopted by the industry and implemented for consumers at large. In order to impart portabilit...
Neonatal Nutrition for Inflammatory Disorders and Necrotizing Enterocolitis
This Nutrients Special Issue focuses on neonatal nutritional advances for inflammatory disorders affecting infants such as necrotizing enterocolitis (NEC). Nutrition can significantly impact the development of certain diseases that afflict infants. This Special Issue aims to bring together the latest research on the role of nutrition in preventing or impacting neonatal disorders. Specifically, this Special Issue focuses on the role of breast milk or donor breast milk and the various components in milk that have been demonstrated to protect against NEC and other inflammatory diseases. This issue provides a comprehensive composite of the advances in nutritional strategies that can modulate or prevent neonatal intestinal disorders.
Handbook of Large-Scale Distributed Computing in Smart Healthcare
This volume offers readers various perspectives and visions for cutting-edge research in ubiquitous healthcare. The topics emphasize large-scale architectures and high performance solutions for smart healthcare, healthcare monitoring using large-scale computing techniques, Internet of Things (IoT) and big data analytics for healthcare, Fog Computing, mobile health, large-scale medical data mining, advanced machine learning methods for mining multidimensional sensor data, smart homes, and resource allocation methods for the BANs. The book contains high quality chapters contributed by leading international researchers working in domains, such as e-Health, pervasive and context-aware computing, cloud, grid, cluster, and big-data computing. We are optimistic that the topics included in this book will provide a multidisciplinary research platform to the researchers, practitioners, and students from biomedical engineering, health informatics, computer science, and computer engineering.
Complexes of Natural Flavonoids with Transition Metals
Human organisms adapted to plant-based diets in hunter-gatherers times. Statistical studies show that people consuming plant products on a regular basis have lower risks of developing cancer and neurodegenerative diseases than people preferably eating starch and fat. The beneficial effects of plants are primarily associated with flavonoids, molecules present in fruits, vegetables, teas, and herbs, also known in traditional medicine for their antibacterial and anti-inflammatory effects. Flavonoids are able to bind metals and form complexes. The present book summarizes the scientific evidence collected over the past decade on the structure, chemistry, and biological function of the complexes of natural flavonoids with nine essential metals representing d-block elements of the periodic table. The role of each individual metal in the human body and the diseases affected by metal-flavonoid complexes are described. The materials collected in the book will be of interest to chemists, biologists, nutritionists, and medicinal scientists.
10 Years of Gastrointestinal and Hepatic Pharmacology
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Botanical Drug Products
Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the safety and effectiveness standards of a new drug in accordance. This book comprises a complete start-to-end process from drug-idea conception, to drug development process. Key Features: Provides a complete compendium for botanical drug products Describes what BDP is and how it differs from Pharma, Biopharma, and Nutraceuticals Compiles all critical regulatory steps in a variety of countries Discusses clinical trial management for BDP development and how it differs from conventional chemical-based drugs and biopharmaceutics
