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As the healthcare environment changes, the need for outcomes-based tre atment planning becomes even more critical. This book guides the reade r through current outcomes-based research as it pertains to surgery. F irst, it gives a complete overview of the practice of evidence-based s urgery (EBS), with topics such as treatment planning, policy issues, a nd ethical issues. Then it gives practical, step-by-step advice on the methodology of EBS, with chapters on study design, outcomes measures, adjustments for complications and comorbidities, cost, and data sourc es. Last, it publishes the results of numerous respected EBS studies.
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Osteonecrosis is a disease caused by reduced blood flow to bones in the joints, including the hip, knee, shoulder, and ankle. The disease, which is usually progressive and leads to joint failure, occurs in young adults aged from their twenties to their fifties. The pathogenesis of osteonecrosis is still unclear, and treatment remains controversial. This textbook provides up-to-date and comprehensive information on the pathophysiology, etiology, diagnosis, classification, and treatment of osteonecrosis. The role of various imaging modalities is considered, and both non-surgical and surgical treatment approaches are clearly explained. The contributions, all from experts in the field, are based on presentations at leading international meetings during the past 10 years and on peer-reviewed papers. The book will be of interest not only to clinical practitioners but also to those engaged in basic research.
Bone circulation is important to our understanding of many major orthopedic conditions such as osteoarthritis, osteoporosis, repair, and tumors. Yet, circulatory physiology, basic to all healthy organs and most diseases, has been difficult to study in the skeleton. The biological regulation of blood flow is complex and the tissues have been relatively inaccessible to measurement. In recent years, however, advances have been made in understanding circulatory physiology and fluid flow in bone, functional measurement of blood flow, and the roles of circulation in bone turnover and repair. These advances have enhanced our insights into bone homeostasis and the interrelationships of circulation and skeletal biology, including repair and disease.This seminal volume presents updated information on circulatory physiology of bone and fluid flow through the bone matrix. It then describes new techniques in quantifying and imaging bone circulation. A clinical section covering circulatory elements of skeletal diseases provides valuable insight into pathophysiology that may serve as diagnostic biomarkers or therapeutic targets.
The biases that permeate the American healthcare system are nearly invisible; invisible to all but those they handicap. In Healthcare and Human Dignity, law professor Frank McClellan recounts the experiences of some such individuals and highlights the importance of establishing a healthcare system that prioritizes human dignity.
This book reviews the current understanding of the mechanical, chemical and biological processes that are responsible for the degradation of a variety of implant materials. All 18 chapters will be written by internationally renowned experts to address both fundamental and practical aspects of research into the field. Different failure mechanisms such as corrosion, fatigue, and wear will be reviewed, together with experimental techniques for monitoring them, either in vitro or in vivo. Procedures for implant retrieval and analysis will be presented. A variety of biomaterials (stainless steels, titanium and its alloys, nitinol, magnesium alloys, polyethylene, biodegradable polymers, silicone gel, hydrogels, calcium phosphates) and medical devices (orthopedic and dental implants, stents, heart valves, breast implants) will be analyzed in detail. The book will serve as a broad reference source for graduate students and researchers studying biomedicine, corrosion, surface science, and electrochemistry.
The second edition of Distinct Identities continues to provide a sophisticated yet accessible introduction to the complexities of the politics, social structures, and cultural contexts that animate how women of color engage in and shape U.S. politics. Keeping the structure of the original volume, this text represents the diverse and innovative scholarship being conducted in this field while covering the core topics in gender politics. What’s New: Chapters on queer women of color and the role of women of color and social movements. Chapters on the strategies that women of color use to run for office, where they run, political newcomers (Asian and Indigenous women). Chapters on the experiences of women of color office holders. Chapters on policy analysis and the media’s role in shaping the political agenda of women of color political elites. Distinct Identities pushes the boundaries of traditional intersectional scholarship and responds to America’s rapidly diversifying demographics and political culture. It reflects cutting-edge scholarship and provides readers with insight into where the field of women of color politics will head in the coming years.