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Melatonin in the Promotion of Health, Second Edition
Designed for researchers, physicians, and lay people interested in the topic, Melatonin in Health Promotion examines virtually all aspects of the multifunctional hormone melatonin, a subject of intense scientific research and general interest. Topics addressed include how melatonin is synthesized; possible harmful side effects; and the role this hormone plays in diseases such as epilepsy, Alzheimer's, and cancer.
The Science and Development of Transport—ZIRP 2021
This monograph presents the original scientific manuscripts submitted for publication at the International Conference - The Science and Development of Transport (ZIRP 2021), organized by the University of Zagreb, Faculty of Transport and Traffic Sciences, Zagreb, Croatia. The Conference takes place in Šibenik, Croatia, from 30th September until 1st October 2021, aiming to bring together the scientists and the practitioners by putting forward innovative solutions available to everyone. This monograph presents the newest scientific research, case studies, and best practices in the field of transport and logistics. In addition to the main topics, many relevant manuscripts in the field of transport and logistics have been presented, such as sustainable urban mobility and logistics, safety and policy, data science, process automation, inventory forecasting, improving competitiveness in the transport and logistics services market and raising customer satisfaction. The monograph will be of interest for the experienced researchers, professionals as well as Ph.D. students in the field of transport and logistics
Bifurcation Stenting
Here is expert guidance on one of the most vexing clinical challenges faced by interventional cardiologists. Written by global thought leaders in the area and edited by two internationally-recognized pioneers in interventional cardiology, Bifurcation Stenting covers all techniques, imaging modalities, and devices in current use, including VH-IVUS and OCT. It includes practical tips/tricks from leading experts and a section of challenging cases to further illustrate the material and help readers better understand the treatment of bifurcation lesions.
Foamy Viruses
The aberrant replication pathway of foamy viruses distinguishes them from all other retroviruses. Many details have been accumulated over the past ten or so years. Most of the findings on foamy viruses were obtained by research on a single virus isolate previously called "human foamy virus", which appeared to be the first to be investigated on a molecular level. However, to the editor's knowledge, genuine human foamy viruses do not exist, but several trans-species transmissions of different simian foamy viruses from monkeys and apes to human hosts.
Clinical Guide to Cardiac Autonomic Tests
Following systematic development of technical aspects and physiological understanding, and clinical applicability of cardiac autonomic testing, this book provides a detailed guide to performing individual autonomic tests in both research and clinical settings. The book is structured in three parts covering the physiological background of cardiac autonomic regulations, description of technology and interpretation of individual autonomic tests, and applicability of the individual tests under various clinical circumstances and in defined populations of patients. The book is intended to serve both research and clinical cardiologists as well as research and clinical specialists of other medical fields who use the assessment of cardiac modulations to investigate the autonomic nervous system.
Radiopharmaceuticals for PET Imaging - Issue A
Positron emission tomography (PET) is a very useful technique for medical diagnosis and drug development. Radiopharmaceuticals are a key element in PET techniques and one of the pivotal factors influencing the applications of PET. The aim of this Special Issue of Molecules is to report on the recent research work on a number of aspects of PET radiopharmaceuticals and their preclinical and clinical use. More specifically, the content of this Special Issue includes but is not limited to radiolabeling design, radiosynthesis, synthesis techniques, quality control methodologies, GMP production methods, product formulation, in vitro and in vivo preclinical PET evaluations, clinical evaluations, dosimetry, stability study and metabolite analysis, and modeling.
Multifractals and Chronic Diseases of the Central Nervous System
This book primarily focuses on the study of various neurological disorders, including Parkinson’s (PD), Huntington (HD), Epilepsy, Alzheimer’s and Motor Neuron Diseases (MND) from a new perspective by analyzing the physiological signals associated with them using non-linear dynamics. The development of nonlinear methods has significantly helped to study complex nonlinear systems in detail by providing accurate and reliable information. The book provides a brief introduction to the central nervous system and its various disorders, their effects on health and quality of life, and their respective courses of treatment, followed by different bioelectrical signals like those detected by Elect...
Medullary Thyroid Carcinoma
This book offers a comprehensive overview of medullary thyroid carcinoma, both in the more common sporadic form and in the familial form, multiple endocrine neoplasia (MEN) types 2A and 2B. The coverage includes, but is not limited to, molecular biology and genetics, pathology, clinical presentation, imaging techniques, surgical treatment, and follow-up. The role of calcitonin as a highly sensitive and specific tumor marker for the screening, diagnosis, and follow-up of MTC and metastatic disease is described, and the significance of other tumor markers is also considered. With regard to treatment, the use of thyroidectomy is fully discussed, including in children carrying the mutations in t...
The Histamine H3 Receptor
In the early eighties when the H3 receptor was identified, many thought that an H3 ligand, an agonist or an antagonist, would become available as a therapeutic agent. This has not occurred. The reason for this could be the fact that many investigators consider histamine mainly, if not only, as a mediator present in for example mast cells being released during allergic events. However, it has become apparent that histamine is an important neurotransmitter. Its role in the nervous system, especially in the central part of it, is rather extensive. The H3 receptor is mainly found as a presynaptic one, both on histaminergic neurons (the auto-type) and on other neuronal systems (the hetero-type). ...
