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Global Mobility of Highly Skilled People
This volume examines self-initiated expatriates (SIEs), the category of highly skilled people whose movement from one country to another is by choice. Although they are not forced to relocate due to work, conflict or natural disaster, their migration pattern is every bit as complex. The book challenges previous theoretical approaches that take for granted a more simplistic view of this population, and advances that mobility of SIEs relates to the expatriates themselves, their conditions and the different structures intervening in their career life course. With their visible increase worldwide, this book positions itself as a nexus for this on-going discussion, while linking self-initiated ex...
Public Health Perspectives on Disability
Traditionally, the public health viewpoint on disability was geared toward primary prevention of disabling conditions or events. More recently, with the movement for disability rights and the emergence of disability studies, the challenge to the field has been to promote positive health outcomes in this underserved community. Such a change in public health culture must start at the educational level, yet training programs have generally been slow in integrating this perspective—with its potential for enriching the field—into their curricula. Public Health Perspectives on Disability meets this challenge with an educational framework for rethinking disability in public health study and pra...
Wearable Monitoring Systems
As diverse as tomorrow’s society constituent groups may be, they will share the common requirements that their life should become safer and healthier, offering higher levels of effectiveness, communication and personal freedom. The key common part to all potential solutions fulfilling these requirements is wearable embedded systems, with longer periods of autonomy, offering wider functionality, more communication possibilities and increased computational power. As electronic and information systems on the human body, their role is to collect relevant physiological information, and to interface between humans and local and/or global information systems. Within this context, there is an incr...
General Farm Program
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The Criminal Act
This volume provides a unique collection of essays in honour of the work of Marcus Felson and his notable contribution to routine activity theory, environmental criminology and the discipline more broadly. Chapter 5 of this book is open access under a CC BY license.
Myotonic Dystrophy
This book provides an essential overview combining both clinical and fundamental research advances in myotonic dystrophy. The pathomechanism of myotonic dystrophy has long been unclear, but in the past decade, our understanding has shifted to a novel disease mechanism concept: “RNA disease”. Parallel to these advances in elucidating the pathophysiology, translational research is also progressing rapidly. The current challenge lies in assessing the effectiveness of treatment, and as such, there is a growing interest in observational studies of the disease’s various clinical symptoms. The book introduces readers to the molecular mechanisms within each organ and the resultant clinical fea...
Jak-Stat Signaling : From Basics to Disease
JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulates essential biological responses to environmental cues. The Jak-Stat pathway is involved in the regulation of cell development, differentiation, proliferation and apoptosis. Improper function may contribute to hematopoietic malignancies and cancer. This book provides comprehensive insights into the latest basic and clinical developments in the field. The first part reviews recent findings and new technologies pertaining to basics of Jak-Stat function. The second part describes the evolution of Jak-Stat signaling and the role of the pathway in invertebrate organisms. The third part focuses on Jak-Stat signaling in hematopoietic cells under both physiological and pathophysiological conditions. Finally, chapters in the fourth section describe the relationship of Jak-Stat signaling to various states of disease, particularly infection, leukemias and solid cancers. The book is intended for all scientists in molecular biology, biochemistry and cell biology dealing with biomedical issues.
U.S. Army Register
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