Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Drug Design
Drug Design, Volume III covers the mode of action of biologically active compounds. The book discusses microbial transformations that have been used in the preparation of drugs or closely related substances; the use of linear free energy parameters and other experimental constants in structure-activity studies; and the mode of action of anticoagulants structurally and functionally related to vitamin K. The text also describes the design of beta-blocking drugs, biologically active acridines, local anesthetics, and insect chemosterilants. The molecular approach for designing inhibitors to enzymes involved in blood clotting is also considered. Chemists, pharmacologists, and people involved in drug design.
Similarity Models in Organic Chemistry, Biochemistry, and Related Fields
Since Hammett devised the rho-sigma equation in 1937, the application of similarity models through linear free energy relationships (correlation analysis) has become increasingly important for systematising the quantitative data of organic chemistry and related fields. More than twelve years have elapsed since the last appearance of a multi-author, international monograph on this subject, during which time there have been substantial developments. Sophisticated chemometric techniques, such as principal component analysis, have been added to the basic statistical techniques of simple and multiple regression. The interaction with quantum mechanics, particularly in the form of ab initio molecul...
Molecular Descriptors for Chemoinformatics, 2 Volume Set
Molecular Descriptors for Chemoinformatics As every chemist knows, there is a direct (if complex) relationship between the molecular structure of a compound and its chemical behavior. Predicting such behavior is possible by an abstract representation of its structure in terms of chemical similarity parameters, socalled ‘descriptors’. These are most useful in predicting the pharmacological properties of drug candidates, but are also used in predicting reactivity, toxicity and other important chemical characteristics. The number-one reference on the topic now contains a wealth of new data: The entire relevant literature over the past eight years has been pain-stakingly surveyed, resulting ...
The Charlton Men
‘The Charlton Men’, the first part of a trilogy set in South London, combines literary fiction with a love of football. Set in the historic surrounds of Greenwich and Charlton, the novel interweaves the rich heritage of the area’s past with contemporary themes of social disenfranchisement and a search for meaning. Set in the aftermath of the 2011 London riots, the story follows two “Charlton Men” as their lives become intertwined with the fortunes of their local football club. Lance, a Londoner, has followed Charlton his whole life – from childhood right up until his return from Afghanistan, scarred by war and feeling abandoned after the sacrifices he has made for his country. Fergus, an Irishman, comes to London to get a fresh start on life and finds himself falling in love not once, but twice – first with the club and the riots, and second with a mysterious Marilyn Monroe lookalike whose darker side ripples beneath the surface. Conflict arises, however, when his friend Lance falls for the same woman and the two men find themselves pitted against one another as competitors for her affection.
Engineering
None
“The” Academy
None
“The” Athenaeum
None
The Pall Mall Budget
None
The Canarian
None
