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This book is a supplement to Volume V/I in the present series, Diag nostie Radiology, published in 1962. Despite the relatively long period of time whieh has elapsed sinee its publieation, that eomprehensive vol urne is still essentially valid, even though further developments have of course oeeurred in eertain fields. In reeent years the developments in nuclear medieine and ultrasonie teehniques have led to a number of new methods of medieal investigation, whieh, in different ways, eomplement diagnostie radiology. Funetional disorders of the urinary traet ean often be detected by means of radioiso topes. Sinee morphologie ehanges are almost always preeeeded by fune tional disturbanees, radi...
This volume reviews current pathophysiologic concepts and describes state-of-the-art techniques for management of cardiac arrhythmias in children and young adults with congenital heart disease. The book provides a thorough understanding of cardiac electrophysiology and detailed technical information on catheter ablation, pacemakers, and implantable defibrillators. Coverage includes a "how-to" chapter on three-dimensional mapping techniques for localizing arrhythmias. A chapter by world-renowned experts examines current treatment options for postoperative atrial tachycardia. The book also includes a review of the anatomy of the cardiac conduction system and a discussion of new findings in molecular genetics that relate to hereditary arrhythmias.
Long QT syndrome is a heart rhythm disorder that can cause fast, chaotic heartbeats. In some cases, long QT syndrome can cause sudden death. Long QT syndrome may result from a genetic mutation or be caused by certain medications and medical conditions. The condition is treatable with medication, surgery, or an implantable device. Because it may have serious consequences, it's important for electrophysiologists to know about long QT syndrome.
This book, now in its fourth edition, aims to promote a deeper understanding of the scientific and clinical basis of nuclear medicine and the new directions in medical imaging. The new edition has been revised and updated significantly to reflect recent changes and to ensure that the contents are in line with likely future directions. In addition to that, chapters have been reorganized in order to simplify the contents and to increase the readability. The book starts by providing essential information on general pathophysiology, cell biology and biologic effects of ionizing radiation followed by the mechanisms of radiopharmaceutical localization in different tissues and cells. This is follow...
Drug Design, Volume VI covers practical approaches to the development of bioactive compounds, with focus on antiradiation agents, organ-imaging radiopharmaceuticals, X-ray contrast media, proteinase inhibitors, and pesticide formulations. The book discusses the chemical routes available for the synthesis of diphenhydramine derivatives, the biological activities, the relationships between structure and activity, and the phase of manipulation in the design of diphenhydramine derivatives. The text also describes the design of antiradiation agents, organ-imaging radiopharmaceuticals, and X-ray contrast media, as well as the rational approach to proteinase inhibitors. The chemical and physical methods of formulation of agricultural pesticides are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design and manufacture will find the book invaluable.
Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and...
The 3rd edition of this classic – considered the standard in the field - reflects the latest advances in PET, SPECT, and oncology. Updated to incorporate cutting-edge diagnostic techniques, it serves as a bedrock resource for physicians whose nuclear medicine practices include children and provides a vast amount of background material for residents in training. The new edition retains the fundamental standard of excellence that earned its predecessors such a distinguished reputation. It has been thoroughly updated to incorporate cutting-edge diagnostic techniques. Pediatric Nuclear Medicine/PET, Third Edition is an indispensable resource for physicians whose practices include children and provides a vast amount of background material for residents in training.
Nuclear medicine is the bridge between a particular clinical problern and a relevant test using radionuclides. It began as a minor technical tool used in a few branches of medicine, notably endocrinology and nephrology. However, throughout the world it has now become established as a clinical discipline in its own right, with specific training programmes, special skills and a particular approach to patient management. Although the practising nuclear medicine physician must necessarily learn a great deal of basic science and technology, a sound medical training and a clinical approach to the subject remains of fundamental importance. It is for this reason that we have attempted in this book t...