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PNH and the GPI-Linked Proteins
Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently it has been acknowledged that PNH is not rare, and once sensitive assays--based on the chemistry of the proteins--can be applied to many patients.Written by international experts in the field, this book includes a number of distinctive characteristics, such as the clinical features of PNH, the mechanism of hemolysis, the biochemistry of glycosylphosphoinositol anchors, and the chemistry and biophysics of GPI-anchored proteins.This unique and timely volume will have a wide audience, including hematologists and oncologists with a clinical interest in this disease, as well as basic biochemists, immunologists, and cell biologists studying this class of proteins. - Outlines the chemical features of PNH - Explains the mechanism of hemolysis - Includes work on the biochemistry of glycophosphoinositol anchors - Contains descriptions of the chemistry and biophysics of GPI-anchored proteins
The High Magic of Talismans and Amulets
A comprehensive study of the use of talismans and amulets in the Western Mystery Tradition • Provides an in-depth look at the medieval and Renaissance use of amulets and talismans, including the work of Agrippa, Albertus Magnus, and Athanasius Kircher • Provides a full summary of the magical knowledge required to make an amulet or talisman, including the invocations required to activate their powers • Reviews different kinds of amulets and talismans, from ancient jewelry and magical objects to the modern rabbit’s foot or lucky horseshoe The use of talismans and amulets stretches back nearly to the dawn of man, from everyday items magically prepared, such as horns or coins, to intrica...
American Trypanosomiasis
Chagas disease causes severe socioeconomic impact and a high medical cost in Latin America. WHO and the World Bank consider Chagas disease as the fourth most transmittable disease to have a major impact on public health in Latin America: 120 million persons are potentially exposed, 16 to 18 million of whom are presently infected, causing 45,000 to 50,000 deaths per year. It has been calculated that approximately 2.4 million potential working years are lost because of incapacity and mortality due to the disease, for an annual cost estimated at 20 billion Euros. American Trypanosomiasis provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease: - The host: human and mammalian reservoirs - The insect vectors: domestic and sylvatic vectors - The causative parasite: Trypanosoma cruzi - Informs and updates on all the latest developments in the field - Contributions from leading authorities and industry experts
Science and Civilisation in China: Volume 5, Chemistry and Chemical Technology, Part 4, Spagyrical Discovery and Invention: Apparatus, Theories and Gifts
The fifth volume of Dr Needham's immense undertaking, like the fourth, is subdivided into parts for ease of assimilation and presentation, each part bound and published separately. The volume as a whole covers the subjects of alchemy, early chemistry, and chemical technology (which includes military invention, especially gunpowder and rockets; paper and printing; textiles; mining and metallurgy; the salt industry; and ceramics).
Science and Civilisation in China: Volume 5, Chemistry and Chemical Technology, Part 5, Spagyrical Discovery and Invention: Physiological Alchemy
The fifth volume of Dr Needham's immense undertaking, like the fourth, is subdivided into parts for ease of assimilation and presentation, each part bound and published separately. The volume as a whole covers the subjects of alchemy, early chemistry, and chemical technology (which includes military invention, especially gunpowder and rockets; paper and printing; textiles; mining and metallurgy; the salt industry; and ceramics).
