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Investigations into the field of immunology are rapidly expanding with the use of genetically altered mice at the embryonic stage. This breakthrough laboratory guide provides a complete study of transgenesis and targeted mutagenesis in laboratory mice that will be valued by researchers looking for fresh observations and interpretations when designing future experiments.Special Features Include:Contributions of two Nobel Prize winnersAddresses the use of mouse models in studying the immune systemTargets gene distribution in embryonic stem cells and their introduction into blastocyte mice modelsAnalyzes the in vivo functional loss of embryonic cellsA practical, useful guidebook for individual researchers, laboratories, and libraries
This book constitutes the proceedings of the 7th Joint International Conference on Service-Oriented Computing, ICSOC-ServiceWave 2009, held in Stockholm, Sweden, in November 2009. The 54 contributions to this volume, consisting of 37 full papers, 8 short papers and 9 demonstration papers, were carefully reviewed and selected from 228 submissions. The papers are arranged in topical sections on composition, discovery, design principles, customization and adaptation, negotiation, agreements and compliance, selection, platforms and infrastructures, security, modeling and design, validation and verification, reputation and ranking, and service management. This volume launches the new subline of Lecture Notes in Computer Science, entitled LNCS Services Science.
This volume contains the proceedings of the NATO Advanced Study Institute held in Porto Conte (Alghero), Sardinia, September 15-27, 1991. The A. S. 1. was attended by 86 graduate and postgraduate students from 18 different countries, and was hosted by the newly founded International Laboratory of Molecular Genetics of Porto Conte, directed by Prof. Marcello Siniscalco. The A. S. I. was funded by NATO Scientific Affairs Division, the International Union of Immunological Societies, the European Community (Directorate General for Science, Research and Development), the Italian Research Council, and the San Raffaele Institute of Milano. In addition, a number of students who reside in the U. S. received travel funds from the U. S. National Science Foundation, and the Turkish National Fund provided financial assistance to several students from Turkey. When we decided to organize a course on T lymphocytes, our concern was to reach a balance between the teaching of both the hard core principles and the latest experimental findings of cellular immunology, and the recently expanded interfaces with the not-yet known: hypotheses, speCUlations, new projections to be born from the discussions.
This book describes a new, “e-Health” approach to stroke rehabilitation. The authors propose an alternative approach that combines state of the art ICT technologies ranging from Augmented and Virtual Reality gaming environments to latest advances in immersive user interfaces for delivering a mixed-reality training platform, along with advanced embedded micro sensing and computing devices exhibiting enhanced power autonomy by using the latest Bluetooth Smart communication interfaces and energy saving approaches. These technologies are integrated under the umbrella of an online Personal Health Record (PHR) services allowing for delivery of personalized, patient-centric medical services whe...