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This book communicates the latest findings in pediatric orthopedics and answers key everyday questions in the field in an informative, readily understandable manner. The scope is comprehensive, encompassing all aspects of diagnosis and therapy. After an opening section on basic principles, the two main sections discuss diseases and injuries by site and cover systemic conditions including trauma, infections, juvenile rheumatoid arthritis, tumors and hereditary diseases. The book is the translation of the latest edition of the well-known classic Kinderorthopädie in der Praxis, which presents the collected knowledge of experts from Basel University Children's Hospital – Fritz Hefti and his c...
A subgroup of homeobox genes, which play an important role in the developmental processes of a variety of multicellular organisms, Hox genes have been shown to play a critical role in vertebrate pattern formation. Hox genes can be thought of as general purpose control genes—that is, they are similar in many organisms and direct the same processes in a variety of organisms, from mouse, to fly, to human. - Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area - Inclusion of chapters that discuss the evolutionary development of a wide variety of organisms - Gives researchers and clinicians insight into how defective Hox genes trigger developmental abnormalities in embryos
The way plants grow and develop organs significantly impacts the overall performance and yield of crop plants. The basic knowledge now available in plant development has the potential to help breeders in generating plants with defined architectural features to improve productivity. Plant translational research effort has steadily increased over the last decade due to the huge increase in the availability of crop genomic resources and Arabidopsis-based sequence annotation systems. However, a consistent gap between fundamental and applied science has yet to be filled. One critical point often brought up is the unreadiness of developmental biologists on one side to foresee agricultural applicat...
Proteomics and peptidomics is the detailed understanding of the role that proteins and peptides play in health and disease and is a necessary compliment to genetic analysis. The functional expression analysis of both proteins and peptides plays a central role in modern drug discovery as well as drug development, and is also a key research area in systems biology. Proteomics and Peptidomics captures the width as well as the depth within the area and exemplifies the variety as well as the traditional basis of analytical chemistry that is needed in order to move forward in expression analysis studies. As a fast emerging field, it gives and overview of parts within the field combined with highly specialized and dedicated topics that are intended to compliment each other.
Intercellular Communication in Plants provides an overview of intercellular signaling systems, capitalizing on the results of contemporary molecular biology. Many biological phenomena are controlled by intercellular signaling systems, initiated by messenger molecules. For example, intercellular communication channels are thought to be associated with a plant's growth and dormancy development - an important adaptive strategy for the survival and regrowth of temperate perennials. This volume is directed at researchers and professionals in plant biochemistry, physiology, cell biology and molecular biology, in both the academic and industrial sectors.
Precise regulation of gene expression in both time and space is vital to plant growth, development and adaptation to biotic and abiotic stress conditions. This is achieved by multiple mechanisms, with perhaps the most important control being exerted at the level of transcription. However, with the recent discovery of microRNAs another ubiquitous mode of gene regulation that occurs at the post-transcriptional level has been identified. MicroRNAs can silence gene expression by targeting complementary or partially complementary mRNAs for degradation or translational inhibition. Recent studies have revealed that microRNAs play fundamental roles in plant growth and development, as well as in adaptation to biotic and abiotic stresses. This book highlights the roles of individual miRNAs that control and regulate diverse aspects of plant processes.
Step-by-step reproducible laboratory procedures written by the top experts in the field offering their time-tested hints, tricks, and tips. Presents detailed outlines of embryonic systems models along with cutting-edge cellular, genetic, and molecular mechanism. Provides the most comprehensive collection of protocols on plan embryo development.
Plant Transcription Factors: Contribution in Development, Metabolism, and Environmental Stress provides comprehensive coverage of plant TFs and their various functions, evaluating their crucial role in growth and development, signaling, stress management and other key plant processes. Sections cover the significance of plant TFs in functional genomics, the influence of phyto-hormones on the modulation of plant TFs, plant development and metabolism, including shoot development, flowering development and alkaloid biosynthesis. The book's final section reviews the role of TFs in various plant stresses, including temperature, water and heavy metal stress. Written by leading experts around the globe, this book is an essential read to researchers interested in plant signaling and plant genomics. - Presents the latest advances in plant transcription factors and their functions - Discusses the influence of phyto-hormones on the modulation of plant transcription factors - Highlights the relationship between plant TFs and plant development
"Double Fertilization" provides a comprehensive overview of all aspects of this central event in the reproduction and development of flowering plants. Written by Val Raghavan, The Ohio State University, an acknowledged expert in plant developmental biology, the book vividly describes the molecular and cellular steps of the unique and complex fertilization process that culminates in the formation of embryo and endosperm, focusing on the latest results from the model plant Arabidopsis. The text is complemented by excellent illustrations, including 16 color plates. Since embryo and endosperm constitute the edible parts of many seeds and grains widely used in human and animal nutrition, an understanding of the fertilization process has great relevance for genetic engineering aimed at improving the nutritional quality of crop plants. This book is ideally suited to researchers and graduate students seeking a coherent view of current perspectives on embryogenesis and endosperm development in flowering plants.
This book provides a multifaceted look into the world of stem cells and explains the similarities and differences between plant and human stem cells. It explores the intersection between animals and plants and explains their cooperative role in bioengineering studies. The book treats both theoretical and practical aspects of stem cell research. It covers the advantages and limitations of many common applications related to stem cells: their sources, categories, engineering of these cells, reprogramming of their functions, and their role as novel cellular therapeutic approach. Written by experts in the field, the book focuses on aspects of stem cells ranging from expansion-propagation to meta...