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Verity Gallant is a lonely little girl who doesn't quite fit in. But when a mysterious stranger hands her an ancient book, everything changes. Suddenly it's up to her to solve the riddle of an ancient pledge and protect her family from the evil Mistress of the Storm. What hope does she have against a witch so powerful she can control the wind and create storms at will? Luckily, Verity does not have to face her enemy alone. As events begin to spiral out of control, she finds two loyal and steadfast friends to stand by her side. The Storm is coming. And it will change Verity's life forever.
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Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Why is there an 'h' in ghost? William Caxton, inventor of the printing press and his Flemish employees are to blame: without a dictionary or style guide to hand in fifteenth century Bruges, the typesetters simply spelled it the way it sounded to their foreign ears, and it stuck. Seventy-five per cent of English spelling is regular but twenty-five per cent is complicated, and in Spell It Out our foremost linguistics expert David Crystal extends a helping hand to the confused and curious alike. He unearths the stories behind the rogue words that confound us, and explains why these peculiarities entered the mainstream, in an epic journey taking in sixth century monks, French and Latin upstarts, the Industrial Revolution and the internet. By learning the history and the principles, Crystal shows how the spellings that break all the rules become easier to get right.
This volume reviews advances in cancer chemotherapy research over the last 10 years. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs. Each chapter covers the drug target and biological rationale, chemotypes, clinical status and future prospects in this rapidly developing area of drug research.
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Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches.