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Neuropsychology of Communication
In this volume, the communicative and neuropsychological correlates of daily interactions are discussed. The predominant account on explaining the construction of meaning by humans is the inter-relational perspective, that postulates an intentional convergence of meaning arising as a consequence of the active exchanges between people. The neural correlates of communication were illustrated in the light of new empirical results, considering the main topics of: a) language and language development; b) pragmatics and neuropragmatics of communication; c) neurocognition and the cognitive bases of intentions; d) nonverbal communication and emotion contribution to the communicative systems. New methodological approaches are considered, with particular attention to neuroimaging (such as PET and fMRI) and brain stimulation techniques (as MEG and TMS), as well as their application to the clinical field.
Textbook of Catheter-Based Cardiovascular Interventions
This book is a fully updated and revised second edition of a highly successful text in which a new concept of knowledge mining, based on explication and transfer of interventional knowledge of experts, has been implemented. The dedicated training program that is set out will serve the needs of all interventional operators, whether cardiologists, vascular surgeons, vascular specialists, or radiologists, enabling them to achieve a consistent expert level across the entire broad spectrum of catheter-based interventions. Operator skills – and in particular decision-making and strategic skills – are the most critical factors for the outcome of catheter-based cardiovascular interventions. Currently, such skills are commonly developed by the empirical trial and error method only. The explicit teaching, training, and learning approach adopted in this book permits the rapid transfer of interventional knowledge and enables individual operators to negotiate steep learning curves and acquire complex skills in a highly efficient manner. It will thereby offer invaluable assistance in meeting successfully the challenges of modern cardiovascular care.
Histamine H4 receptor
H4 R is the newest member of the histamine receptor family, which was discovered about twelve years ago. It is considered a very promising drug target. The effort to improve the pharmacokinetic properties of the currently available H4 R ligands is reflected in a steadily growing number of scientific publications and patent applications. Preclinical data strongly confirms the need for novel potent H4 R ligands to explore their therapeutic value in allergy, inflammation, autoimmune disorders, and possibly, cancer. Readers will be provided with extensive knowledge on histamine metabolism, as well as cellular histamine transport, storage and release, effects of histamine and histamine receptor ligands, with particular attention to the H4 R, on inflammatory cells including mast cells, basophils, eosinophils, neutrophils, macrophages, dendritic cells, and T cells. The present knowledge on the regulatory role of histamine and the therapeutic exploitation of histamine receptor ligands in atopic diseases, with emphasis on human and animal models of asthma, allergic dermatitis and pruritus are discussed.
Genetics and Evolution of Infectious Diseases
Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pa...
Bioactive Heterocycles IV
With contributions by numerous experts
Fluoroplastics
Fluoropolymers were discovered accidentally by Plunkett in 1938. He was working on freon and accidentally polymerised tetrafluoroethylene. The result was polytetrafluoroethylene (PTFE), more commonly known as Teflon. PTFE is inert to virtually all chemicals and is considered to be the most slippery material in existence - it has the lowest coefficient of friction of any known solid material. These properties have made it one of the most valuable and versatile technologies ever invented, contributing to significant advancements in areas such as aerospace, communications, electronics, industrial.
The Genetics of African Populations in Health and Disease
A pioneering work that focuses on the unique diversity of African genetics, offering insights into human biology and genetic approaches.
