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In recent years there has been a steadily increasing cross-fertilization between cosmology and particle physics, on both the theoretical and experimental levels. Particle physics has provided new experimental data from the big accelerators in operation, and data from space satellites are accumulating rapidly. Cosmology is still one of the best laboratories for testing particle theory. The present work discusses such matters in the context of inflation, strings, dark matter, neutrinos and gravitational wave physics in the very early universe, field theory at the Planck scale, and high energy physics. A particular emphasis has been placed on a new topology for spatial infinity, on the relation between temperature and gravitational potential, a canonical formulation of general relativity, the neutrino mass, spin in the early universe, the measurement of gravity in the 10--100 m range, galaxy--galaxy and cluster--cluster correlation, black holes, string theory and string/string duality. The work also presents a beautiful review of high energy elementary particle physics, treating the meaning, status and perspectives of unification and standard model gauge couplings.
The field of nuclear medicine has evolved rapidly in recent years, and one very important aspect of this progress has been the introduction of hybrid imaging systems. PET-CT has already gained widespread acceptance in many clinical settings, especially within oncology, and now SPECT-CT promises to emulate its success. Useful applications of this new approach have been identified not only in oncology but also in endocrinology, cardiology, internal medicine, and other specialties. This atlas, which includes hundreds of high-quality images, is a user-friendly guide to the optimal use and interpretation of SPECT-CT. The full range of potential SPECT-CT applications in clinical routine is considered and assessed by acknowledged experts. The book is designed to serve as a reference text for both nuclear physicians and radiologists; it will also provide fundamental support for radiographers, technologists, and nuclear medicine and radiology residents.
This book represents an up-dated summary of the state of the art of the characterization of cancer stem cell/ cancer initiating cell (CSC/CIC) properties. An overview of the definition and biological properties of CSCs/CICs as well as the role of these cells in determining the resistance to standard and immune-based therapies is provided. It also discusses limitations in the achievement of a definitive biological characterization of CSCs/CICs due to their high extent of plasticity and heterogeneity that is also mutually driven by the interaction of these cells with the tumor microenvironment. The limitations in targeting CSCs/CICs with immunotherapy are also explained together with explorati...
The concepts of dark matter and the cosmic web are some of the most significant developments in cosmology in the past century. They have decisively changed the classical cosmological paradigm, which was first elaborated upon during the first half of the 20th century but ran into serious problems in the second half. Today, they are integral parts of modern cosmology, which explains everything from the Big Bang to inflation to the large-scale structure of the Universe.Dark Matter and Cosmic Web Story describes the contributions that led to a paradigm shift from the Eastern point of view. It describes the problems with the classical view, the attempts to solve them, the difficulties encountered...
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This study is devoted to the Sunyaev-Zeldovich (S-Z) effect, and important related topics in cluster and CMB research. S-Z science is about to be significantly enhanced by unique, multi-faceted cluster and cosmological yield, at a level of precision in accord with the high standards of the current era that was heralded by spectacular achievements in cosmological CMB research. The pedagogical reviews and technical seminars included in this volume represent most of the important current topics in S-Z work and in the astrophysics of clusters. The publication touches upon all relevant aspects of the S-Z effect and its use as a precise cluster and cosmological probe. To commemorate the 40th anniversary of the detection of the CMB by Penzias and Wilson (in 1964), there is a chapter devoted to the history of this discovery. In his fascinating account of their work, he outlines also some lessons pertinent to current scientific issues. Other chapters discuss very interesting related observational work in Europe and the US.
This book brings together contributions from internationally renowned experts in the biochip field. The authors present not only their latest research work, but also discuss current trends in biochip technology. Specific topics range from microarray technology and its applications to lab-on-a-chip technology.