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Peptide and Protein Drug Delivery
This reference/text covers fundamentals of peptide and protein drug delivery, including such considerations as synthesis, physical chemistry and biochemistry, analysis, proteolytic and transport constraints, pharmacokinetics, and pharmacodynamics; bioavailability from routes of administration, detai
Current Trends in Connectionism
In order to build "intelligent" machines, many researchers have turned to the only naturally occurring intelligent system: the brain. For quite a while now, both the function and architecture of the brain have served as inspiration to philosophers, psychologists, computer scientists, neurobiologists, physicists and others in their quest for solving problems that seem to require intelligence in their own particular domain. The progress in the field of connectionism -- or artificial neural networks -- has had its ups and downs during its maturing years. Advocates of the field pointed out the virtues of connectionist systems, dealing with low-level cognitive tasks such as visual recognition and...
Introducing Biological Rhythms
Introducing Biological Rhythms is a primer that serves to introduce individuals to the area of biological rhythms. It describes the major characteristics and discusses the implications and applications of these rhythms, while citing scientific results and references. Also, the primer includes essays that provide in-depth historic and other background information for those interested in more specific topics or concepts. It covers a basic cross-section of the field of chronobiology clearly enough so that it can be understood by a novice, or an undergraduate student, but that it would also be sufficiently technical and detailed for the scientist.
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Biologic Rhythms in Clinical and Laboratory Medicine
Everyone has heard of nature's "biological clocks", the phenomenon of periodic activity in plants, animals and humans. But what does chronobiology have to do with modern medicine? This book presents in a concise but comprehensive fashion the basic principles of chronobiology and their application to clinical medicine. The chapters are written by specialists in the field; they summarize the physiology, pathophysiology and pathology of the human time structure and outline the application of chronobiologic principles and techniques for diagnosis and treatment.
Understanding Models for Learning and Instruction:
The pioneering research and theories of Norbert Seel have had a profound impact on educational thought in mathematics. In this special tribute, an international panel of researchers presents the current state of model-based education: its research, methodology, and technology. Fifteen stimulating, sometimes playful chapters link the multiple ways of constructing knowledge to the complex real world of skill development. This synthesis of latest innovations and fresh perspectives on classic constructs makes the book cutting-edge reading for the researchers and educators in mathematics instruction building the next generation of educational models.
Independent review of police officer and staff remuneration and conditions
This review began on 1 October 2010 and the reviewer, Tom Winsor, was asked to ensure that police pay and conditions and the structures around them are the best they could be given the challenges currently facing the police service. Budget cuts will see forces being required to achieve more with less, but also need to be fair to officers and staff. The review is to report in two parts, covering short-term and long-term improvements. This is Part one and covers: the deployment of officers and staff (including shift allowances, overtime and assisting other police forces); post and performance related pay (including special priority payments, competence related threshold payments for constables...
