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Advancing Progress in the Development of Combination Cancer Therapies with Immune Checkpoint Inhibitors
In recent years, significant progress has been made in the clinical development and use of various types of cancer immunotherapy, all of which rely on the immune system to fight cancer. The majority of new cancer drug applications submitted to the Food and Drug Administration (FDA) are for immunotherapies or combinations involving immunotherapies. One type of immunotherapy is an immune checkpoint inhibitor. Cells in the human body have proteins that regulate the immune system response to foreign invaders (e.g., cancer cells, microorganisms). However, cancer cells can coopt these "checkpoint" proteins and thwart the immune system's ability to recognize and attack cancer cells. To help promote...
Flavour Science
This volume contains the 86 lectures, posters and workshop presentations made at the 8th Weurman Flavour Research Symposium. These are mainly research papers and are divided into seven subject areas reflecting the major divisions of flavour science.
Metabloism of Nutrients by Gut Microbiota
Bringing together expert researchers in the fields of microbiome, metabolism, and nutrition research, this book compiles the current state of knowledge from authorities specifically on how diet regulates microbial function with metabolic implications for the human host. Chapters cover the broad concepts of microbial-host interactions under the dietary influences of specific macronutrients, micronutrients, small molecule generation and bile acid circulation, with inclusion of later clinical chapters encompassing topics like bariatric surgery and our current understanding of probiotics, prebiotics, and synbiotics. Covering a timely topic from a functional standpoint, the book fills a gap in the existing literature. While increased attention is placed on descriptive work, it will importantly highlight emerging functional and mechanistic research findings that illustrate the inner workings of the dietary-microbial-host orchestration of metabolic regulation. Providing an exciting summary of the importance of current microbial function, it will also summarize the next major directions in the field of microbiome research.
Flavour and Fragrance Chemistry
The volume deals with several aspects of the chemistry of both synthetic and natural organic compounds related to flavours and fragrances. It presents very recent results, some of them previously unpublished, and findings related to the chemistry of flavours and fragrances. It is organized in four sections: flavours and fragrances of foodstuffs, essential oils and other natural products from plants, applied aspects of flavour and fragrance production and detection, analytical aspects of flavour and fragrance isolation and identification. It should be of interest to academic and applied scientists in the field of organic chemistry, phytochemistry, analytical chemistry and food science.
Compound-Nuclear Reactions
The Compound-Nuclear Reaction and Related Topics (CNR*) international workshop series was initiated in 2007 with a meeting near Yosemite National Park. It has since been held in Bordeaux (2009), Prague (2011), Sao Paulo (2013), Tokyo (2015), and Berkeley, California (2018). The workshop series brings together experts in nuclear theory, experiment, data evaluations, and applications, and fosters interactions among these groups. Topics of interest include: nuclear reaction mechanisms, optical model, direct reactions and the compound nucleus, pre-equilibrium reactions, fusion and fission, cross section measurements (direct and indirect methods), Hauser-Feshbach theory (limits and extensions), compound-nuclear decays, particle and gamma emission, level densities, strength functions, nuclear structure for compound-nuclear reactions, nuclear energy, nuclear astrophysics, and other topics. This peer-reviewed proceedings volume presents papers and poster summaries from the 6th International Workshop on Compound-Nuclear Reactions and Related Topics CNR*18, held on September 24-28, 2018, at Lawrence Berkeley National Lab, Berkeley, CA.
They Eat Our Sweat
Accounts of corruption in Africa and the Global South are generally overly simplistic and macro-oriented, and commonly disconnect everyday (petty) corruption from political (grand) corruption. In contrast to this tendency, They Eat Our Sweat offers a fresh and engaging look at the corruption complex in Africa through a micro analysis of its informal transport sector, where collusion between state and nonstate actors is most rife. Focusing on Lagos, Nigeria's commercial capital and Africa's largest city, Daniel Agbiboa investigates the workaday world of road transport operators as refracted through the extortion racket and violence of transport unions acting in complicity with the state. Stee...
Alou
Growing up in a tiny shack in the Dominican Republic, Felipe Alou never dreamed he would be the first man born and raised in his country to play and manage in Major League Baseball—and also the first to play in the World Series. In this extraordinary autobiography, Alou tells of his real dream to become a doctor, and an improbable turn of events that led to the pro contract. Battling racism in the United States and political turmoil in his home country, Alou persevered, paving the way for his brothers and scores of other Dominicans, including his son Moisés. Alou played seventeen years in the Major Leagues, accumulating more than two thousand hits and two hundred home runs, and then managed for another fourteen years—four with the San Francisco Giants and ten with the Montreal Expos, where he became the winningest manager in franchise history. Alou’s pioneering journey is embedded in the history of baseball, the Dominican Republic, and a remarkable family.
Volatile Biomarkers for Human Health
This book offers an outlook into the challenges in the continuing development of volatile biomarkers and their wider availability to healthcare research and industries.
Food Flavor and Chemistry
The rapidly evolving field of food flavor chemistry holds an important role in a wide variety of food and beverage products. Food Flavor and Chemistry: Explorations into the 21st Century provides the reader with an update on the advances in food chemistry and flavor science with a broad spectrum of food products from both plants and animals. Topics covered also include: Dairy products and wine flavors Formation of flavors Tenderization of meat Migration of chemicals in food packaging Antioxidants and health Quality control The biotechnical generation of aromas is addressed in depth and new technical information on sensory evaluation and on analytical techniques are covered. Theories of quality development based on scientific research are presented as well as research that will lead to enhanced food quality. Food Flavor and Chemistry: Explorations into the 21st Century will be of interest to a broad spectrum of workers advancing flavor chemistry, food product research and development as well as those in the quality control area.
South Vietnam
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