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Handbook of Growth Factors
Volume I of this book provides a comprehensive discussion of the factors involved in regulation of the cell cycle, the general biological properties of growth factors, and the receptor and postreceptor mechanisms of action of these signaling agents. It evaluates the possible role of growth factors in the regulation of proto-oncogene and tumor suppressor gene expression, and the development of neoplastic processes is discussed in detail.
Advanced Catalysts Based on Metal-organic Frameworks (Part 2)
Advanced Catalysts Based on Metal-organic Frameworks is a comprehensive introduction to advanced catalysts based on MOFs. It covers basic information about MOF catalysts with industrial and environmental applications. The detailed chapters update readers on current applications and strategies to apply MOF-based catalysts in industrial processes geared for sustainability initiatives such as renewable energy, pollution control and combating carbon emissions. Key Features of Part 2 - 7 structured, easy to read chapters that comprehensively cover specific applications of MOF catalysts- In-depth explanation of photocatalytic reactions for multifunctional electrocatalysis, water splitting and CO2 Capture - Notes on MOF materials used in modern processes - Explanation of MOFs in advanced oxidation reactions - Introduction to Electrochemical biosensors - Updated references for advanced readers The is an essential reference for chemical engineers, scientists in the manufacturing and sustainability industry and post-graduate scholars working on MOFs and chemical catalysis.
Mass Spectrometry Handbook
Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.
Neurosteroids
Thirty years ago, the group of Baulieu and colleagues discovered that certain steroid hormones were present in higher amounts in the brain than in the plasma, and also found that suppression of circulating steroids by adrenalectomy and castration did not affect the concentration of pregnenolone, dehydroepiandrosterone and their sulfate esters in the rat brain. These seminal observations led to the concept that the brain, in very much the same way as the adrenal cortex, testis, ovary and placenta, was capable of synthesizing steroids. These brain born steroids, called neurosteroids, have been found to exert a vast array of biological activities. A number of steroidogenic enzymes have now been identified in the central nervous system by immunohistochemistry and in situ hybridization, and the neuronal and hormonal mechanisms regulating the biosynthesis of neurosteroids have been partially elucidated. The aim of this Research Topic is to celebrate three decades of research on neurosteroids by gathering a bouquet of review papers and original articles from leading scientists in the flourishing field of neurosteroids.
Neurosteroid Effects in the Central Nervous System
Presenting a complete overview of the effects of steroid hormones in the brain and describing new methods for investigating these effects, this book discusses theories on steroid action in the central nervous system and the techniques for receptor localization and quantification and enzyme regulation. The author explores the use of transgenic/antisense strategies to determine sites and the cellular effects of steroid action in the brain. He covers steroid action on mood, cognition, sensorimotor action, neuroprotection, and plasticity, and describes methods using molecular, electrophysical, and behavioral techniques to link cellular mechanisms of steroid action with behavioral effects.
Hormones in Neurodegeneration, Neuroprotection, and Neurogenesis
As life expectancy increases and population ages, the already enormous impact of neurodegeneration on society will become even larger without better prevention and treatment. Developing strategies to prevent degeneration of neurons and to promote a healthy nervous system is, thus, critical. The development of pharmacological agents that would increase production of new neurons was recently facilitated by the identification of the hormonal regulators of various steps of adult neurogenesis. The proposed book is writen by a group of top world experts involved in the study of the mechanisms of hormonal control of brain damage and repair. The effects of thyroid and steroid hormones (estrogens, an...
DHEA and the Brain
DHEA and the Brain reviews a range of existing studies regarding DHEA administration to animals and humans. Chapter authors evaluate DHEA metabolism in tissues and organs, explore DHEA effects in the liver that may be of importance to the brain, and discuss recent findings regarding how DHEA is made in the brain. New perspectives about the neuropro
Handbook of Research on Healthcare Standards, Policies, and Reform
The healthcare industry has been the center of attention recently as it continues to have a major impact on private and public organizations, government institutions, and consumers. An increasing number of requests for healthcare has led to the implementation of new policies and reform proposals that are challenging as they can have a simultaneous impact on different categories of users. As many health, individual, and organizational activities continue to grow and are conducted in the general environment, new vulnerabilities have emerged that have led to the need to study the system from a different angle. The nature, source, and complexity of healthcare is not always clear, and many times ...
Climate Change and Ecosystems
The global population is projected to increase by 3.3 billion from 6.7 billion in 2008 to 10 billion in 2100. As a result, soil degradation and desertification are growing due to the increasing demand for food, feed, fiber, and fuel on finite soil resources. The problem of global food insecurity may be further worsened by the threat of global warming. Climate change is showing its impacts in terms of increasing temperatures, variable rainfall, and an increase in climate-related extremes such as floods, droughts, cyclones, sea-level rise, salinity, and soil erosion. The agriculture sector is the most sensitive to climate change because the climate of a region/country determines the nature and...
