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N.A.E.S. Agencia para el estudio del espacio
Tras recibir un mensaje del otro lado del universo, los dirigentes mundiales se ven forzados a colaborar para descifrarlo pero, como siempre, no todos juegan limpio. El propio proceso de traducción entraña sus riesgo, ya que uno de los grupos destinados a tal tarea se verá en grave peligro debiendo trabajar de forma estrecha no solo para lograr su objetivo, sino para salvar sus vidas. Fruto de la interpretación del comunicado recibido, la humanidad se embarca en un proyecto de dimensiones titánicas, cuya meta es la de contactar con una civilización desconocida, desarrollando una misión que les llevará más allá de lo imaginable, afrontando grandes dificultades, pues las amenazas no provendrán únicamente del exterior...
Topology of Algebraic Varieties and Singularities
This volume contains four parts which look at algebraic geometry and fundamental groups, braids and knots, hyperplane arrangements and singularities.
Stress Echocardiography
This sixth edition is enriched by over 300 figures, 150 tables and a video-companion collecting more than 100 cases also presented in the format of short movies and teaching cartoons. This extensively revised and enlarged edition of this long-seller documents the very significant advances made since the fifth (2009) edition and is entirely written by Eugenio Picano, a pioneer in the field sharing his lifetime experience with the help of an international panel of 50 contributors from 22 countries representing some of the best available knowledge and expertise in their respective field. In a societal and economic climate of increasing pressure for appropriate, justified and optimized imaging, ...
Muscle Atrophy
The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thi...
Life's Philosophy
Now available in English for the first time, Norwegian philosopher Arne Naess's meditation on the art of living is an exhortation to preserve the environment and biodiversity. As Naess approaches his ninetieth year, he offers a bright and bold perspective on the power of feelings to move us away from ecological and cultural degradation toward sound, future-focused policy and action. Naess acknowledges the powerlessness of the intellect without the heart, and, like Thoreau before him, he rejects the Cartesian notion of mind-body separation. He advocates instead for the integration of reason and emotion--a combination Naess believes will inspire us to make changes for the better. Playful and s...
Exon Skipping and Inclusion Therapies
This book presents a comprehensive collection of detailed state-of-the-art exon skipping and splices modulation protocols. Chapters detail 14 genetic diseases, AON-mediated therapies, and CRISPR/Cas9-mediated gene editing therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Exon Skipping and Inclusion Therapies: Methods and Protocols aims to help researchers initiate the development of next-generation therapies.
