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GI Microbiota and Regulation of the Immune System
This book covers current trends in the investigation of GI microbiota. It examines the relationship between the microbiota and the immune system from a variety of angles.
Candida and Candidiasis
The underlying mechanisms of Candida and candidiasis and promising new directions in drug discovery and treatment. • Reviews all aspects of this common fungal pathogen and its impact on human health, from the basic biology of Candida albicans to the clinical management of candidiasis. • Reviews the latest basic and clinical research, focusing on findings in genome variability, host-pathogen interactions, antifungal resistance and drug discovery, and diagnostics to foster better understanding and treatment of candidiasis. • Examines recent discoveries that have shed light on morphogenesis and the cell cycle, including how new findings on host responses may have applications for the diagnosis of blood-borne candidiasis.
An Epidemic of Absence
A controversial, revisionist approach to autoimmune and allergic disorders considers the perspective that the human immune system has been disabled by twentieth-century hygiene and medical practices.
Cellular Oscillatory Mechanisms
Oscillatory dynamics are a central feature of a wide range of biological processes. This text fully explores cellular oscillations, focusing particularly on elucidating the basic mechanisms that underlie these oscillations.
Somitogenesis
This book will be of interest to scientists working in the fields of cell and developmental biology. The chapters cover topics that capture the spirit of this dynamic discipline by integrating contemporary research with the classical embryological literature.
Molds, Mushrooms, and Medicines
The hidden role of fungi inside and all around us From beneficial yeasts that aid digestion to toxic molds that cause disease, we are constantly navigating a world filled with fungi. Molds, Mushrooms, and Medicines explores the amazing ways fungi interact with our bodies, showing how our health and well-being depend on an immense ecosystem of yeasts and molds inside and all around us. Nicholas Money takes readers on a guided tour of a marvelous unseen realm, describing how our immune systems are engaged in continuous conversation with the teeming mycobiome inside the body, and how we can fall prey to serious and even life-threatening infections when this peaceful coexistence is disturbed. He...
Multichain Immune Recognition Receptor Signaling
This book shows how the structural similarity of MIRRs determines the general principles underlying MIRR-mediated transmembrane signaling mechanisms. In so doing, it provides the basis for existing and future therapeutic strategies targeting MIRRs.
Molecular Mechanisms of Xeroderma Pigmentosum
Xeroderma pigmentosum (XP), meaning parchment skin and pigmentary dist- bance, is a rare and mostly autosomal recessive genetic disorder that was originally named by two dermatologists, the Austrian Ferdinand Ritter von Hebra and his H- garian son in law Moritz Kaposi in 1874i and 1883. 2 The earliest published record (PubMed) available on the internet is a publication in 1949 by Ulicna Zapletalova under the title, "Contribution to the pathogenesis of xeroderma pigmentosum". It was in the late 1960s when James Cleaver (contributor of Chapter 1 of this book), at the University of California, San Francisco, while working on nucleotide excision repair (NER), read an article in a local newspaper...
The Sarcomere and Skeletal Muscle Disease
Although best known for its role in heart disease, the sarcomere--the fundamental unit of muscle contraction--is also involved in skeletal muscle diseases. Chapters in The Sarcomere and Skeletal Muscle Disease provide an up-to-date review of diseases caused by mutated proteins in the different sub-compartments of the sarcomere, document the techniques currently being used to investigate the pathobiological bases of the diseases, which remain largely unknown, and discuss possible therapeutic options.
