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Down Syndrome
Down syndrome, the most cutting-edge book in the field congenital disorders. This book features up-to-date, well referenced research and review articles on Down syndrome. Research workers, scientists, medical graduates and pediatricians will find it to be an excellent source for references and review. It is hoped that such individuals will view this book as a resource that can be consulted during all stages of their research and clinical investigations. Key features of this book are: Common diseases in Down syndrome Molecular Genetics Neurological Disorders Prenatal Diagnosis and Genetic Counselling Whilst aimed primarily at research workers on Down syndrome, we hope that the appeal of this book will extend beyond the narrow confines of academic interest and be of interest to a wider audience, especially parents, relatives and health-care providers who work with infants and children with Down syndrome.
Social Environment and Cancer in Europe
This contributed volume addresses the link between the social environment and cancer in Europe. The authors document the wide range and diverse trends in cancer incidence and patient survival in Europe, and they identify the main mechanisms and key influences that underlie these inequalities. They suggest a series of actions and programmes to tackle these inequalities in Europe, within the conceptual framework of intervention research. The influence of the social environment on the risk of suffering and dying from cancer is obviously a global phenomenon, as evidenced by a growing number of studies and books. In part, the underlying mechanisms are universal. Given the availability of a new st...
Genetics and Etiology of Down Syndrome
This book provides a concise yet comprehensive source of current information on Down syndrome. Research workers, scientists, medical graduates and paediatricians will find it an excellent source for reference and review. This book has been divided into four sections, beginning with the Genetics and Etiology and ending with Prenatal Diagnosis and Screening. Inside, you will find state-of-the-art information on: 1. Genetics and Etiology 2. Down syndrome Model 3. Neurologic, Urologic, Dental
Handbook of Survival Analysis
Handbook of Survival Analysis presents modern techniques and research problems in lifetime data analysis. This area of statistics deals with time-to-event data that is complicated by censoring and the dynamic nature of events occurring in time. With chapters written by leading researchers in the field, the handbook focuses on advances in survival analysis techniques, covering classical and Bayesian approaches. It gives a complete overview of the current status of survival analysis and should inspire further research in the field. Accessible to a wide range of readers, the book provides: An introduction to various areas in survival analysis for graduate students and novices A reference to modern investigations into survival analysis for more established researchers A text or supplement for a second or advanced course in survival analysis A useful guide to statistical methods for analyzing survival data experiments for practicing statisticians
Presidential Activism and Veto Power in Central and Eastern Europe
This book examines the use of presidential powers in Central and East Europe between 1990 and 2010. Focussing on presidential vetoes and the formation of governments, it maps patterns of presidential activism and its determinants across nine democracies. Thereby, it combines the analysis of original quantitative data on the use of presidential powers with in-depth case studies in an innovative mixed-methods framework. Based on regression analyses and unique insights from numerous elite interviews, the study shows strong support for the hitherto insufficiently tested assumption that popularly elected presidents are more active than their indirectly elected counterparts. As one of the first comprehensive comparative studies of presidential activism and veto power in Europe, this book will be a key resource not only for area specialists but also for scholars of presidential studies, comparative government, and executives.
Bayesian Approaches in Oncology Using R and OpenBUGS
Bayesian Approaches in Oncology Using R and OpenBUGS serves two audiences: those who are familiar with the theory and applications of bayesian approach and wish to learn or enhance their skills in R and OpenBUGS, and those who are enrolled in R and OpenBUGS-based course for bayesian approach implementation. For those who have never used R/OpenBUGS, the book begins with a self-contained introduction to R that lays the foundation for later chapters. Many books on the bayesian approach and the statistical analysis are advanced, and many are theoretical. While most of them do cover the objective, the fact remains that data analysis can not be performed without actually doing it, and this means u...
Hands-On Ensemble Learning with R
Explore powerful R packages to create predictive models using ensemble methods Key Features Implement machine learning algorithms to build ensemble-efficient models Explore powerful R packages to create predictive models using ensemble methods Learn to build ensemble models on large datasets using a practical approach Book Description Ensemble techniques are used for combining two or more similar or dissimilar machine learning algorithms to create a stronger model. Such a model delivers superior prediction power and can give your datasets a boost in accuracy. Hands-On Ensemble Learning with R begins with the important statistical resampling methods. You will then walk through the central tri...
Medical Risk Prediction Models
Medical Risk Prediction Models: With Ties to Machine Learning is a hands-on book for clinicians, epidemiologists, and professional statisticians who need to make or evaluate a statistical prediction model based on data. The subject of the book is the patient’s individualized probability of a medical event within a given time horizon. Gerds and Kattan describe the mathematical details of making and evaluating a statistical prediction model in a highly pedagogical manner while avoiding mathematical notation. Read this book when you are in doubt about whether a Cox regression model predicts better than a random survival forest. Features: All you need to know to correctly make an online risk c...
DAGStat 2022
Das Buch enthält die Abstracts der eingeladenen bzw. angenommenen Vorträge der 6. Konferenz der Deutschen Arbeitsgemeinschaft Statistik (DAGStat), welche vom 28. März bis 1. April 2022 am Universitätsklinikum Hamburg-Eppendorf (UKE) in Kooperation mit der Universität Hamburg sowie der Helmut-Schmidt-Universität stattfand. Die Konferenz stellte ebenfalls das 68. Biometrische Kolloquium der Deutschen Region der International Biometric Society (IBS-DR) dar, sowie die 45. Jahrestagung der Gesellschaft für Klassifikation (GfKl/Data Science Society). Die Vorträge behandelten dabei ein breites Spektrum sowohl angewandter als auch eher methodischer/theoretischer Themen aus dem Bereich Statistik und Data Science.
Flexible Parametric Survival Analysis Using Stata
Through real-world case studies, this book shows how to use Stata to estimate a class of flexible parametric survival models. It discusses the modeling of time-dependent and continuous covariates and looks at how relative survival can be used to measure mortality associated with a particular disease when the cause of death has not been recorded. The book describes simple quantification of differences between any two covariate patterns through calculation of time-dependent hazard ratios, hazard differences, and survival differences.
