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Role of Epigenetic Modifications on Diet-Induced Metabolic Diseases
  • Language: en
  • Pages: 180

Role of Epigenetic Modifications on Diet-Induced Metabolic Diseases

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Molecular Nutrition
  • Language: en
  • Pages: 450

Molecular Nutrition

Molecular Nutrition: Mother and Infant presents the impact of diet in early life stages, from pre-conception, throughout pregnancy, and to the infant. The book covers the molecular biology of the cell, genetic machinery and its function, general coverage on diet and nutrition, pregnancy, placenta, weight gain, breast milk, feeding practices, gestational disease, glucose metabolism, immunity, vitamins and minerals. Other topics discusses include fetal programming, bioactive compounds, amino acids, intrauterine growth, one carbon metabolism, overnutrition, genetic risk factors, polymorphisms, folic acid genes, DNA methylation, genes involved in lipid metabolism, microRNAs, epigenetics, transcr...

Genome Editing in Cardiovascular and Metabolic Diseases
  • Language: en
  • Pages: 338

Genome Editing in Cardiovascular and Metabolic Diseases

This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in cardiovascular diseases, genome editing in metabolic diseases and therapeutic effects. It will be useful for biologist, cardiologist, cardiovascular surgeons, endocrinologist, internists, nurses, undergraduate and graduate students in medicine and cell biology and others interested in cardiovascular and metabolic medicine.

Protein Metabolism and Homeostasis in Aging
  • Language: en
  • Pages: 268

Protein Metabolism and Homeostasis in Aging

Aging is loosely defined as the accumulation of changes in an organism over time. At the cellular level such changes are distinct and multidimensional: DNA replication ceases, cells stop dividing, they become senescent and eventually die. DNA metabolism and chromosomal maintenance, together with protein metabolism are critical in the aging process. The focus of this book is on the role of protein metabolism and homeostasis in aging. An overview is provided of the current knowledge in the area, including protein synthesis, accuracy and repair, post-translational modifications, degradation and turnover, and how they define and influence aging. The chapters mainly focus on well-characterised fa...

Advances in Stem Cell Research
  • Language: en
  • Pages: 398

Advances in Stem Cell Research

Advances in Stem Cell Research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

JIMD Reports, Volume 18
  • Language: en
  • Pages: 138

JIMD Reports, Volume 18

  • Type: Book
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  • Published: 2015-03-16
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  • Publisher: Springer

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

Precision Nutrition and Metabolic Syndrome Management
  • Language: en
  • Pages: 223

Precision Nutrition and Metabolic Syndrome Management

  • Type: Book
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  • Published: 2018-08-21
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  • Publisher: MDPI

This book is a printed edition of the Special Issue "Precision Nutrition and Metabolic Syndrome Management" that was published in Nutrients

Immunohistochemical Expression
  • Language: en
  • Pages: 168

Immunohistochemical Expression

  • Type: Book
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  • Published: 2021-09-02
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  • Publisher: MDPI

Immunohistochemistry (IHC) is an ancillary method, widely used in pathologists’ practice, that allows identifying diagnostic and prognostic/predictive of therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies and chromogenic substances that guarantee the visualization of an antibody–antigene binding complex under a light microscope [1]. Coon et al., in 1941 [2], first introduced the use of fluorochrome-conjugated antibodies in clinical practice. Since then, IHC has gone from being a useful tool for identifying the differentiation line of otherwise undifferentiated cells to a technique capable of providing not only diagnostic but also prognostic and predictive indications of responses to specific therapeutic options [1,3]. The abovementioned peculiarities have made IHC one of the most used ancillary methods in the histopathological approach to human neoplastic and non-neoplastic diseases [3-5]. This Special Issue contains 11 accepted papers that provide readers with a comprehensive update on current and future applications of IHC in medical practice.

MUSCLE PHYSIOLOGY
  • Language: en
  • Pages: 164

MUSCLE PHYSIOLOGY

Embark on a captivating journey into the dynamic world of Muscle Physiology with our specialized guide. Tailored for students, researchers, and fitness enthusiasts, "Muscle Physiology" is a comprehensive book that unravels the intricacies of muscular systems. Enriched with in-depth insights, practical knowledge, and extensive Multiple-Choice Question (MCQ) practice, this guide is designed to deepen your understanding of muscle function, performance, and health. Key Features: Mechanisms of Muscle Contraction: Delve into the molecular and cellular processes that govern muscle contraction. "Muscle Physiology" provides a thorough exploration of the mechanisms, including the role of actin, myosin...

The Longevity Seekers
  • Language: en
  • Pages: 240

The Longevity Seekers

People have searched for the fountain of youth everywhere from Bimini to St. Augustine. But for a steadfast group of scientists, the secret to a long life lies elsewhere: in the lowly lab worm. By suppressing the function of just a few key genes, these scientists were able to lengthen worms’ lifespans up to tenfold, while also controlling the onset of many of the physical problems that beset old age. As the global population ages, the potential impact of this discovery on society is vast—as is the potential for profit. With The Longevity Seekers, science writer Ted Anton takes readers inside this tale that began with worms and branched out to snare innovative minds from California to Cre...