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The Role of Mitochondria, Oxidative Stress and Altered Calcium Homeostasis in Amyotrophic Lateral Sclerosis: From Current Developments in the Laboratory to Clinical Treatments
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive, devastating and fatal disease characterized by selective loss of upper and lower motor neurons of the cerebral cortex, brainstem, spinal cord and muscle atrophy. In spite of many years of research, the pathogenesis of ALS is still not well understood. ALS is a multifaceted genetic disease, in which genetic susceptibility to motor neuron death interacts with environmental factors and there is still no cure for this deleterious disease. At present, there is only one FDA approved drug, Riluzole which according to past studies only modestly slows the progression of the disease, and improves survival by up to three months. The sufferin...
Intelligent Computing Applications for Sustainable Real-World Systems
This book delves into various solution paradigms such as artificial neural network, support vector machine, wavelet transforms, evolutionary computing, swarm intelligence. During the last decade, novel solution technologies based on human and species intelligence have gained immense popularity due to their flexible and unconventional approach. New analytical tools are also being developed to handle big data processing and smart decision making. The idea behind compiling this work is to familiarize researchers, academicians, industry persons and students with various applications of intelligent techniques for producing sustainable, cost-effective and robust solutions of frequently encountered complex, real-world problems in engineering and science disciplines. The practical problems in smart grids, communication, waste management, elimination of harmful elements from nature, etc., are identified, and smart and optimal solutions are proposed.
Technological Eco-Innovations for the Quality Control and the Decontamination of Polluted Waters and Soils
The Special Issue “Technological Eco-Innovations for the Quality Control and the Decontamination of Polluted Waters and Soils” deals with the most recent research activities carried out at lab and field scale on eco-sustainable tools for the remediation of contaminated environmental substrates. It is particularly devoted to highlight the relevance of biological organisms (plants, microbes, algae) to assess the chemical contamination in water and soil and to remediate such matrices from the pollution caused by the human activities. Therefore, bioremediation is a primary focus of most of the articles published within the present Special Issue. Bioremediation is a promising environmentally ...
Lions 322E District Directory
Print Edition of Lions District 322E Directory for the year 2016-17 is released by District Governor Lion Anupam Singhania. This Digital Edition is replica of the same, to enable portability of the book through Mobile Phones. It also saves plenty of Paper and saves Trees.
Biomedicen and Beatitude
This timely and up to date new edition of Biomedicine and Beatitude features an entirely new chapter on the ethics of bodily modification. It is also updated throughout to reflect the pontificate of Pope Francis, recent concerns including ethical issues raised by the COVID-19 pandemic, and feedback from the many instructors who used the first edition in the classroom.
Innovative Design and Development Practices in Aerospace and Automotive Engineering
The book presents the best articles presented by researchers, academicians and industrial experts in the International Conference on “Innovative Design and Development Practices in Aerospace and Automotive Engineering (I-DAD 2016)”. The book discusses new concept designs, analysis and manufacturing technologies, where more swing is for improved performance through specific and/or multifunctional linguistic design aspects to downsize the system, improve weight to strength ratio, fuel efficiency, better operational capability at room and elevated temperatures, reduced wear and tear, NVH aspects while balancing the challenges of beyond Euro IV/Barat Stage IV emission norms, Greenhouse effects and recyclable materials. The innovative methods discussed in the book will serve as a reference material for educational and research organizations, as well as industry, to take up challenging projects of mutual interest.
One Health Implications of Agrochemicals and their Sustainable Alternatives
This book focuses on the United Nations SDG 3, SDG 12, and SDG 15. The book covers the full range of issues associated with agrochemical use from a One Health standpoint to promote a cleaner and safer alternative that leaves little to no negative legacy on Earth’s natural, social, and economic systems. The main focus of the book is to address the biodiversity and human health, food security, and socio-environmental implications of agrochemical use in food production. It deals with the need to move away from the use of harmful chemicals in agriculture. The threat to key aspects of One Health will be used as evidence in support of the need to transition to safer and cleaner food production s...
Integrative Advances in Rice Research
This book describes some recent advances in rice research in terms of crop breeding and improvement (Section 1), crop production and protection (Section 2), and crop quality control and food processing (Section 3). It contains fourteen chapters that cover such topics as two-line rice breeding in India, the different aspects of aromatic rice, bacterial diseases of rice, quality control and breeding strategies, and much more. This volume is a useful reference for professionals and graduate students working in all areas of rice science and technology.
