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This book documents the most important clinicopathological features of rare thyroid tumours with an emphasis (and ample documentation) on their histological and immunohistochemical aspects. Whenever necessary, namely for differential diagnosis and/or therapy purposes, molecular data are also highlighted. In order to understand the histogenesis of rare lesions and to be able to make a differential diagnosis, the editors use the WHO book for endocrine tumours (in preparation) as a framework for classifying thyroid tumours. In addition to characterizing the main histotypes of thyroid tumours, this book also provides detailed information on how to approach the diagnosis of tumours according to the major morphological/immunohistochemical characteristics, the predominant morphology and whether or not they are hereditary. This book is a valuable learning tool for those involved in the differential diagnosis of thyroid lesions.
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Experts from Europe, Japan and the United States have contributed to this in-depth volume on digestive disease pathology. Each chapter contains numerous electron micrographs, often supplemented byline drawings, and extensive references to the literature.The clear illustrations and text are an excellent aid for the diagnosis of pathological entities in the gastrointestinal tract.
Zusammenfassung: This is the third edition of a well-received book that recapitulates the thyroid fine-needle aspiration (FNA) cytology. It covers the basics and critical principles of thyroid cytopathology, addresses technical aspects, and presents the latest breakthrough events in the field, including the new editions of the WHO classification of thyroid tumors and the Bethesda system for reporting thyroid cytopathology. Thyroid FNA Cytology, The Third Edition is a practical handbook for cytopathologists, pathologists, cytotechnologists, endocrinologists, thyroid surgeons, radiologists, thyroid cancer patients, and their families. This edition covers more topics than the previous editions and invites authors from 20 countries from Asia, Europe, and America. It should serve as an individualized guide to readers practicing in various geographic areas with different medical settings and social resources. The book provides multiple chapters on differential diagnosis and pitfalls to show the unique approaches in many countries. The book will broaden their perspectives and serve as a foundation for further advancement in this field
The mechanistic target of rapamycin (mTOR) is a major signaling intermediary that coordinates favorable environmental conditions with cell growth. Indeed, as part of two functionally distinct protein complexes, named mTORC1 and mTORC2, mTOR regulates a variety of cellular processes, including protein, lipid, and nucleotide synthesis, as well as autophagy. Over the last two decades, major molecular advances have been made in mTOR signaling and have revealed the complexity of the events implicated in mTOR function and regulation. In parallel, the role of mTOR in diverse pathological conditions has also been identified, including in cancer, hamartoma, neurological, and metabolic diseases. Through a series of articles, this book focuses on the role played by mTOR in cellular processes, metabolism in particular, and highlights a panel of human diseases for which mTOR inhibition provides or might provide benefits. It also addresses future studies needed to further characterize the role of mTOR in selected disorders, which will help design novel therapeutic approaches. It is therefore intended for everyone who has an interest in mTOR biology and its application in human pathologies.
First multi-year cumulation covers six years: 1965-70.
This book provides a comprehensive description of the pathology of the head and neck region, concentrating especially on those pathologic entities that are unique to or characteristic of the head and neck. The new edition retains the ten chapters of the first edition, all updated and improved, and additionally contains seven entirely new chapters and a more detailed subject index. The number of illustrations has been substantially increased, and various lesions absent in the original edition have been included. Throughout, attention is paid to correlation of pathology with epidemiology, clinical features, pathogenesis, and molecular genetics. Differential diagnosis is addressed, and information is also provided on staging, prognosis, and therapy. The authors include foremost experts in the field, some of whom are senior members of the Working Group on Head and Neck Pathology of the European Society of Pathology.
The first comprehensive surgical pathology textbook and reference on the thyroid in over fifteen years, this book presents the most advanced concepts on the diagnostic surgical pathology, cytopathology, immunohistochemistry, and molecular genetics of neoplastic and non-neoplastic thyroid diseases. The authors provide a detailed description of the surgical pathology of thyroid diseases side-by-side with major advances in immunohistochemistry and molecular genetics that can be used in evaluating thyroid tumors and non-neoplastic diseases. By combining diagnostic surgical pathology, cytopathology, immunohistochemistry, and molecular genetics, the book effectively mimics the practice of contemporary surgical pathologists. All major chapters have a uniform style of description and include a separate section on molecular genetics. A companion Website will include the fully searchable text and an image bank.
Rosai and Ackerman’s Surgical Pathology delivers the authoritative guidance you need to overcome virtually any challenge in surgical pathology. Recognized globally for his unmatched expertise, preeminent specialist Juan Rosai, MD brings you state-of-the-art coverage of the latest advancements in immunohistochemistry, genetics, molecular biology, prognostic/predictive markers, and much more - equipping you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities. Efficiently review the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, differential diagnosis, therapy, and prognosis for virtuall...