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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
INCLUDING RECIPES FROM JAMIE'S HIT CHANNEL 4 TV SHOW KEEP COOKING FAMILY FAVOURITES Make everyday meals more exciting with the No. 1 bestselling cookbook, featuring 120 exciting and tasty new recipes _______ Jamie has done his research to find out exactly what we, as a nation, love to eat. He's taken 18 of our favourite ingredients and created 7 new, easy and delicious ways to cook them. We're talking about those meal staples we pick up without thinking - chicken breast, salmon fillet, mince, eggs, potatoes, broccoli, mushrooms, to name but a few. Jamie will share 7 achievable, exciting and tasty ways to cook each of these hero foods, requiring minimal time, effort and a maximum of only 8 in...
Luffy and his crew arrive in the kingdom of Dressrosa where Doflamingo has prepared a clever trap for them. Can Trafalgar Law get them out of trouble? And will Luffy win the fighting tournament and claim the prize, his late brother’s Flame-Flame Fruit? -- VIZ Media
Longlisted for the 2020 Andrew Carnegie Medals for Excellence A provocative, exuberant novel about time, memory, desire, and the imagination from the internationally bestselling and prizewinning author of The Blazing World, Memories of the Future tells the story of a young Midwestern woman’s first year in New York City in the late 1970s and her obsession with her mysterious neighbor, Lucy Brite. As she listens to Lucy through the thin walls of her dilapidated building, S.H., aka “Minnesota,” transcribes her neighbor’s bizarre and increasingly ominous monologues in a notebook, along with sundry other adventures, until one frightening night when Lucy bursts into her apartment on a resc...
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The first Pan-American Conference on Soil Mechanics and Geotechnical Engineering (PCSMGE) was held in Mexico in 1959. Every 4 years since then, PCSMGE has brought together the geotechnical engineering community from all over the world to discuss the problems, solutions and future challenges facing this engineering sector. Sixty years after the first conference, the 2019 edition returns to Mexico. This book, Geotechnical Engineering in the XXI Century: Lessons learned and future challenges, presents the proceedings of the XVI Pan-American Conference on Soil Mechanics and Geotechnical Engineering (XVI PCSMGE), held in Cancun, Mexico, from 17 – 20 November 2019. Of the 393 full papers submitt...
Este libro contiene 350 cuentos de 50 autores clásicos, premiados y notables. Elegida sabiamente por el crítico literario August Nemo para la serie de libros 7 Mejores Cuentos, esta antología contiene los cuentos de los siguientes escritores: - Abraham Valdelomar - Antón Chéjov - Antonio de Trueba - Arturo Reyes - Baldomero Lillo - César Vallejo - Charles Perrault - Edgar Allan Poe - Emilia Pardo Bazán - Fray Mocho - Gustavo Adolfo Bécquer - Horacio Quiroga - Joaquín Díaz Garcés - Joaquín Dicenta - José Martí - José Ortega Munilla - Juan Valera - Julia de Asensi - Leonid Andréiev - Leopoldo Alas - Leopoldo Lugones - Oscar Wilde - Ricardo Güiraldes - Roberto Arlt - Roberto Payró - Rubén Darío - Soledad Acosta de Samper - Teodoro Baró - Vicente Blasco Ibáñez - Washington Irving - Alfred de Musset - Marqués de Sade - Saki - Marcel Schwob - Iván Turguéniev - Julio Verne - Émile Zola - Villiers de L'Isle Adam - Mark Twain - León Tolstoi - Ryunosuke Akutagawa - Ambrose Bierce - Mijaíl Bulgákov - Lewis Carroll - Arthur Conan Doyle - James Joyce - Franz Kafka - H. P. Lovecraft - Machado de Assis - Guy de Maupassant
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Con la coordinaci n de Mario Roberto Morales, en esta edici n cr tica colaboran estudiosos de talla internacional como Martin Lienhard, Ana Merino e Isabel Arredondo. la intenci n, como lo apunta Jean-Philippe Barnab , otro de los colaboradores, no es recopilar la totalidad de los relatos breves de Asturias, "sino m s bien destacar el car cter en cierto modo circular de su itinerario creativo, mostrando la insistencia con que esta (re)creaci n gen rica llamada leyenda, que inaugura su producci n, vuelve a aparecer en los tramos finales de su carrera".