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How aging affects T lymphocyte-mediated immunity
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The Aging Immune System and Health
The world population presents an increased percentage of individuals over 65 years old and the fastest growing subgroup is over 85 years old. The increase in life expectancy observed in the last century has not been synonymous with extra years lived in good health (disability-free years). Population studies have shown that as individuals age, they can present a great heterogeneity of ability and health. Therefore, aging has been associated for some individuals with disabilities and hospitalizations. Deaths related to infectious pathogens are increased in the aging population mainly due to pneumonia and influenza whereas Cytomegalovirus, Epstein-Barr virus, among other viruses seem to contrib...
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Current Advances in Exercise Immunology
Maintaining optimal immune function is at the cornerstone of disease prevention and management. The realization that lifestyle factors such as exercise, nutrition, sleep and stress can be targeted to optimize immune function for the prevention and treatment of illness and disease has intensified among physicians and health care providers. Exercise immunology as a discipline came to the fore in the early 1990’s through formation of the International Society of Exercise and Immunology (ISEI). Since then, several major advances have been made including the understanding that: (i) physical activity is associated with fewer incidences and symptoms of infection; (ii) every bout of exercise facilitates the ongoing exchange of immune cells between the blood and tissues to increase immune surveillance; (iii) regular exercise lowers chronic low-grade inflammation and improves vaccine responses in the elderly; (iv) contracting skeletal muscle acts as an immune regulatory organ; (v) physical activity can improve immune markers in aging and multiple disease states (e.g. cancer, HIV, diabetes); (vi) exercise expedites infection resolution and restricts host-pathogen entry and dissemination.
Chiral Building Blocks in Asymmetric Synthesis
Chiral Building Blocks in Asymmetric Synthesis A comprehensive introduction to the important classes of chiral building blocks Chirality — the asymmetric quality found in certain chemical compounds — plays an essential role in our world: chiral compounds can be found in biology, pharmaceutical compounds, agrochemicals, and fragrances. The stereoselective preparation of these complex molecular constructions constitutes a challenge. To this end, modern asymmetric synthesis utilizes a variety of valuable and efficient reagents employed as chiral auxiliaries, metal complexes and organocatalysts in stereoselective catalysis, and enantiopure reactants termed as chiral building blocks. In Chira...
PSP94, what is it good for?
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Firestein & Kelley’s Textbook of Rheumatology
With its comprehensive, global coverage of all aspects of diagnosis, screening, and treatment in both adults and children, Firestein & Kelley’s Textbook of Rheumatology remains your reference of choice in this evolving field. The fully revised 12th Edition retains the user-friendly, full color format, providing in-depth guidance in rheumatology with an ideal balance of basic science and clinical application. New editors, new chapters, and new illustrations keep you fully up to date on recent advances in genetics and the microbiome, current therapies, and other rapid changes in the field. Covers everything from basic science, immunology, anatomy, and physiology to diagnostic tests, procedur...
