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Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book inc...
A comprehensive overview of post-traumatic epilepsy and its management, long-term consequences, and the rehabilitation needs of patients. Covering the neurobiology, epidemiology, and the neuropsychiatric aspects of traumatic brain injuries, special populations such as paediatric patients and athletes with concussive injuries are also discussed.
This book is an up-to-date, comprehensive review of the neuropsychiatry of epilepsy, by active authorities in the field, with an emphasis on clinical and management issues. A critical appraisal of the methodology and limitations of current research on the neuropsychiatry of epilepsy is provided, and unanswered questions and controversies are addressed. Pharmacological aspects of management are also discussed in order to enable the reader to manage these patients more safely. Neuropsychiatric Symptoms of Epilepsy is aimed at neurologists, epileptologists, psychiatrists and neuropsychiatrists, and will also be of interest to psychologists and neuropsychologists, research and specialist nurses, clinical researchers and methodologists.
This book reviews the use of antiepileptic drugs focusing on the interactions between these drugs and between antiepileptics and other drugs. These interactions can be beneficial or can cause harm. The aim of this book is to increase awareness of the possible impact of combination pharmacotherapies. Pharmacokinetic and pharmacodynamic interactions are discussed supported by clinical and experimental data. The book consists of five sections covering the general concepts and advantages of combination therapies, the principles of drug interactions, the mechanisms of interactions, drug interactions in specific populations or in patients with co-morbid health conditions, and concludes with a look at the future directions for this field of research. The book will be of interest to all who prescribe antiepileptics to epileptic and non-epileptic patients, including epileptologists, neurologists, neuro-pediatricians, psychiatrists and general practitioners.
Discover the haunting, untold true story of Mary Eleanor Pearcey, whose crimes inspired speculation that Jack the Ripper was a woman. Woman at the Devil's Door is a thrilling look at a notorious murderer and the webs she wove.
This is the first comprehensive two-volume collection on anhedonia, a disorder that played an important role in psychopathology theories at the beginning of the twentieth century. Anhedonia is a condition in which the capacity of pleasure is partially or completely lost, and it refers to both a personality trait, and a “state symptom” in various neuropsychiatric and physical disorders. It has a putative neural substrate, originating in the dopaminergic mesolimbic and mesocortical reward circuit. Over the past three decades cognitive psychology and behavioral neuroscience have expanded our understanding of anhedonia and other reward-related processes. The aim of this new two-volume collec...
Designed to be a practical reference guide, chapters succinctly provide a current overview of the relevant area while concise enough to be read in a single sitting. All of the major co-morbidities of epilepsy are reviewed, as well as the impact of anti-epileptic medications and other therapies. In addition, a specific chapter about older patients with epilepsy is also included. This book supplies the reader with a deeper understanding of the relevant co-morbidities in epilepsy as well as providing insights into strategies to help in the holistic treatment of patients. While primarily UK-focused it will also be of interest to medical/nursing practitioners around the globe, including in the developing world, and to epilepsy charities and interested lay- readers/patients.
This is the first comprehensive two-volume collection on anhedonia, a disorder that played an important role in psychopathology theories at the beginning of the twentieth century. Anhedonia is a condition in which the capacity of pleasure is partially or completely lost, and it refers to both a personality trait, and a “state symptom” in various neuropsychiatric and physical disorders. It has a putative neural substrate, originating in the dopaminergic mesolimbic and mesocortical reward circuit. Over the past three decades cognitive psychology and behavioral neuroscience have expanded our understanding of anhedonia and other reward-related processes. The aim of this new two-volume collec...
Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures, and is complemented by an online edition.
The field of epilepsy and behavior has grown considerably in the past number of years, reflecting advances in the laboratory and clinic. Behavioral Aspects of Epilepsy: Principles and Practice is the definitive text on epilepsy behavioral issues, from basic science to clinical applications, for all neurologists, psychosocial specialists, and researchers in the fields of epilepsy, neuroscience, and psychology/psychiatry. Behavioral aspects of epilepsy include a patient's experiences during seizures, his or her reaction during and between seizures, the frequency of episodes and what can be determined from the number of seizures. With contributions by dozens of leading international experts, th...