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Mitochondria Biology
Methods in Cell Biology Volume 155 provides an update on the step-by-step "how-to" methods to study mitochondrial structure, function and biogenesis contained in the first two editions. As in the previous editions, biochemical, cell biological, and genetic approaches are presented along with sample results, interpretations, and pitfalls for each method. New chapters in this update include Isolation of Mitochondria and Analysis of Mitochondrial Compartments, Isolation of Mitochondria from Animal Cells and Yeast, Isolation and Characterization of Mitochondria-Associated ER Membranes, Import of Proteins into Mitochondria, Proximity Labeling Methods to Assess Protein-Protein Interactions in Yeast Mitochondria, and more.
The Human Mitochondrial Genome
The Human Mitochondrial Genome: From Basic Biology to Disease offers a comprehensive, up-to-date examination of human mitochondrial genomics, connecting basic research to translational medicine across a range of disease types. Here, international experts discuss the essential biology of human mitochondrial DNA (mtDNA), including its maintenance, repair, segregation, and heredity. Furthermore, mtDNA evolution and exploitation, mutations, methods, and models for functional studies of mtDNA are dealt with. Disease discussion is accompanied by approaches for treatment strategies, with disease areas discussed including cancer, neurodegenerative, age-related, mtDNA depletion, deletion, and point m...
Technology, Crafting and Artisanal Networks in the Greek and Roman World
This volume aims to merge theoretical models with methodological approaches on ceramic technology and artisanal networks in the Classical world. This convergence of analytical frameworks allowed scholars to explore some traditional archaeological topics that usually have a very low-level of visibility, such as the skillful gestures of the craftspeople involved, the organization of the ceramic production, the dynamics of apprenticeship and knowledge transfer as well as intra and inter-regional artisanal mobility, in the Graeco-Roman ‘communities of practice’. The papers promote interdisciplinary dialogues among various fields of study, such as archaeology, archaeometry, anthropology, ethnoarchaeology, experimental archaeology, and digital humanities - such as Social Network Analysis, computational imaging, and big data analysis.
The Roman Villa in the Mediterranean Basin
This volume offers a comprehensive survey of Roman villas in Italy and the Mediterranean provinces of the Roman Empire, from their origins to the collapse of the Empire. The architecture of villas could be humble or grand, and sometimes luxurious. Villas were most often farms where wine, olive oil, cereals, and manufactured goods, among other products, were produced. They were also venues for hospitality, conversation, and thinking on pagan, and ultimately Christian, themes. Villas spread as the Empire grew. Like towns and cities, they became the means of power and assimilation, just as infrastructure, such as aqueducts and bridges, was transforming the Mediterranean into a Roman sea. The distinctive Roman/Italian villa type was transferred to the provinces, resulting in Mediterranean-wide culture of rural dwelling and work that further unified the Empire.
Regional Urban Systems in the Roman World, 150 BCE - 250 CE
The focus of Regional Urban Systems in the Roman World is on urban hierarchies and interactions in large geographical areas rather than on individual cities. Based on a painstaking examination of archaeological and epigraphic evidence relating to more than 1,000 cities, the volume offers comprehensive reconstructions of the urban systems of Roman Gaul, North Africa, Sicily, Greece and Asia Minor. In addition it examines the transformation of the settlement systems of the Iberian Peninsula and the central and northern Balkan following the imposition of Roman rule. Throughout the volume regional urban configurations are examined from a rich variety of perspectives, ranging from climate and landscape, administration and politics, economic interactions and social relationships all the way to region-specific ways of shaping the townscapes of individual cities.
From Hydrology to Hydroarchaeology in the Ancient Mediterranean
This volume is devoted to the study of water management in ancient cities. It compares the approaches and methods adopted by researchers from different disciplinary sectors to identify the water conditions of past societies and to highlight the measures they have taken to adapt to their water resources.
Muscle Biopsy
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