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Cardiovascular and Metabolic Comorbidities in Pituitary Disorders
Pituitary disorders may be associated with an increased risk of cardiovascular and metabolic complications and, in consequence, increased mortality. Excessive secretion of pituitary hormones provokes functional and systemic abnormalities which can be manifested by cardiovascular complications such as eg. arterial hypertension, heart failure, arrhythmia, as through metabolic disturbances, including obesity and diabetes. Subclinical effects of pituitary diseases, such as cardiac and vascular dysfunction, also modifies prognosis but due to its asymptomatic course are frequently diagnosed with significant time delay. Even successful surgery and pharmacological treatment of pituitary disorders do...
New Prognostic and Predictive Markers in Cancer Progression
Biomarkers are of critical medical importance for oncologists, allowing them to predict and detect disease and to determine the best course of action for cancer patient care. Prognostic markers are used to evaluate a patient’s outcome and cancer recurrence probability after initial interventions such as surgery or drug treatments and, hence, to select follow-up and further treatment strategies. On the other hand, predictive markers are increasingly being used to evaluate the probability of benefit from clinical intervention(s), driving personalized medicine. Evolving technologies and the increasing availability of “multiomics” data are leading to the selection of numerous potential bio...
Change Your Diet, Change Your Mind
Combine the surprising truth about brain food with the cutting-edge science of brain metabolism to achieve extraordinary improvements to your emotional, cognitive, and physical health. Are you struggling with attention problems, mood swings, food obsession, or depression? Whatever the issue, you have far more control over your thoughts, feelings, and behavior than you realize. Although medications may bring some relief, in Change Your Diet, Change Your Mind, Dr. Georgia Ede reveals that the most powerful way to change brain chemistry is with food, because that’s where brain chemicals come from in the first place. In this provocative, illuminating guide, Dr. Ede explains why nearly every...
Big Problems
A smart, funny dive into the weight-loss industry, from a journalist on a quest to master healthy living Like many of us, Andy Boyle struggled with his weight all his life. But it wasn't until one fateful pants-splitting incident that he realized he really ought to do something about it. Since then he has lost the weight. And put it back on. And lost it again. As he fumbled through his weight-loss journey, Andy learned the hard way that there's a difference between real, effective methods and the crap that big businesses are trying to sell you. In Big Problems, Andy explores the reasons why we've gotten fat in the first place as well as real ways to lose those extra pounds. Through interview...
