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The Porphyrin Handbook
The Porphyrin Handbook, Volume 16: Phthalocyanines: Spectroscopic and Electrochemical Characterization provides information pertinent to every aspect of the chemistry, synthesis, spectroscopy, and structure of phthalocyanines. This book examines the biology and medical implications of porphyrin systems. Organized into five chapters, this volume begins with an overview of the photophysical properties of phthalocyanines that are important in relation to photosensitizers in photodynamic therapy, photoconductor, solar cells, and artificial photosynthesis. This text then describe how the data obtained from magnetic circular dichroism spectroscopy has provided the critical information required to describe the excited and ground state degeneracies of main group metallophthalocyanines complexes. Other chapters consider the electrocatalysis by electrodes modified with phthalocyanine sensors and complexes. This book discusses as well the properties of phthalocyanines and of their complexes. The final chapter deals with the experiments with organic pigment thin films. This book is a valuable resource for research scientists, engineers, and clinicians.
The Porphyrin Handbook
The Porphyrin Handbook, Volume 11: Bioinorganic and Bioorganic Chemistry presents the fundamental aspects of the synthesis, structure, chemistry, and spectroscopy of phthalocyanines. This book discusses the biology and medical implications of porphyrin systems. Organized into seven chapters, this volume begins with an overview of the design, synthesis, and study of the structural and functional models of heme/copper terminal oxidases. This text then examines the proteins containing iron-protoporphyrin IX (heme), which play key roles in photosynthesis and respiration. Other chapters consider the syntheses of chiral porphyrin derivatives and summarize the uses of such compounds in enantioselective control. This book discusses as well the reactivity and synthesis of synthetic carbine metalloporphyrins. The final chapter deals with the B12-coenzymes, which is the most complex and physiologically important organometallic enzymatic reactions that directly depend on the reactivity of metal coordinated organic ligands. This book is a valuable resource for research scientists, clinicians, and engineers.
Biosensing
We have come to know that our ability to survive and grow as a nation to a very large degree depends upon our scientific progress. Moreover, it is not enough simply to keep abreast of the rest of the world in scientific matters. 1 We must maintain our leadership. President Harry Truman spoke those words in 1950, in the aftermath of World War II and in the midst of the Cold War. Indeed, the scientific and engineering leadership of the United States and its allies in the twentieth century played key roles in the successful outcomes of both World War II and the Cold War, sparing the world the twin horrors of fascism and totalitarian communism, and fueling the economic prosperity that followed. Today, as the United States and its allies once again find themselves at war, President Truman’s words ring as true as they did a half-century ago. The goal set out in the Truman Administration of maintaining leadership in science has remained the policy of the U.S. Government to this day: Dr. John Marburger, the Director of the Office of Science and Technology (OSTP) in the Executive Office of the President made remarks to that effect during his confirmation hearings in October 2 2001.
Globalization and WMD Proliferation
This edited volume explores the relationship between the accelerating process of globalization and the proliferation of Weapons of Mass Destruction, which is increasingly seen as the pre-eminent threat to international security. The proliferation of Weapons of Mass Destruction has traditionally been seen as a function of the 'security dilemma' in the state-based international system. But the advent of the nuclear supply network pieced together by the Pakistani scientist A. Q. Khan represented a departure from this model, involving a variety of organizations not directly connected to a state. This volume assembles an international group of experts in order to assess the relationship between p...
New Technologies and the Law of Armed Conflict
Modern technological development has been both rapid and fundamentally transformative of the means and methods of warfare, and of the broader environment in which warfare is conducted. In many cases, technological development has been stimulated by, and dedicated to, addressing military requirements. On other occasions, technological developments outside the military sphere affect or inform the conduct of warfare and military expectations. The introduction of new technologies such as information technology, space technologies, nanotechnology and robotic technologies into our civil life, and into warfare, is expected to influence the application and interpretation of the existing rules of the law of armed conflict. In this book, scholars and practitioners working in the fields critically examine the potential legal challenges arising from the use of new technologies and future directions of legal development in light of the specific characteristics and challenges each technology presents with regard to foreseeable humanitarian impacts upon the battlespace.
The Porphyrin Handbook, Volume 3
Scientists in such fields as mathematics, physics, chemistry, biochemistry, biology, and medicine are currently involved in investigations of porphyrins and their numerous analogues and derivatives. Porphyrins are being used as platforms for the study of theoretical principles, as catalysts, as drugs, as electronic devices, and as spectroscopic probes in biology and medicine. The need for an up-to-date and authoritative treatise on the porphyrin system has met with universal acclaim amongst scientists and investigators.
Dual Use Research of Concern in the Life Sciences
The potential misuse of advances in life sciences research is raising concerns about national security threats. Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies examines the U.S. strategy for reducing biosecurity risks in life sciences research and considers mechanisms that would allow researchers to manage the dissemination of the results of research while mitigating the potential for harm to national security.
The Fourth Industrial Revolution and Military-Civil Fusion
Advanced commercial technologies offer new opportunities for defense applications that could greatly affect military power and metrics of military advantage. This is relevant when it comes to civilian-based technological innovations found in the emerging 'fourth industrial revolution,' such as artificial intelligence, autonomous systems, 'big data,' and quantum computing. Militaries and governments around the world are increasingly focused on how and where advanced commercial technologies, innovations, and breakthroughs could potentially create new capacities for military power, advantage, and leverage. This process of exploiting civilian-based advanced technologies is referred to as 'military–civil fusion' (MCF). This book addresses MCF not only from a conceptual and practical sense but also comparatively as it explores how four different countries – the United States, China, India, and Israel – are attempting to use MCF to support national military-technological innovation. It will interest scholars, researchers, and advanced students of military, security, and technology studies, as well as analysts and policymakers in military and defense organizations.
Innovation, Dual Use, and Security
A framework for assessing the security risks of emerging dual-use technologies and devising tailored governance strategies is proposed and applied to contemporary case studies. Recent advances in disciplines such as biotechnology, nanotechnology, and neuropharmacology entail a “dual-use dilemma” because they promise benefits for human health and welfare yet pose the risk of misuse for hostile purposes. The emerging field of synthetic genomics, for example, can produce custom DNA molecules for life-saving drugs but also makes possible the creation of deadly viral agents for biological warfare or terrorism. The challenge for policymakers is to prevent the misuse of these new technologies w...
