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Methuselah Flies
Methuselah Flies presents a trailblazing project on the biology of aging. It describes research on the first organisms to have their lifespan increased, and their aging slowed, by hereditary manipulation. These organisms are fruit flies from the species Drosophila melanogaster, the great workhorse of genetics. Michael Rose and his colleagues have been able to double the lifespan of these insects, and improved their health in numerous respects as well. The study of these flies with postponed aging is one of the best means we have of understanding, and ultimately achieving, the postponement of aging in humans. As such, the carefully presented detail of this book will be of value to research devoted to the understanding and control of aging. Methuselah Flies: is a tightly edited distillation of twenty years of work by many scientists; contains the original publications regarding the longer-lived fruit flies; offers commentaries on each of the topics covered - new, short essays that put the individual research papers in a wider context; gives full access to the original data; captures the scientific significance of postponed aging for a wide academic audience.
Reticulate Evolution
Written for non-experts, this volume introduces the mechanisms that underlie reticulate evolution. Chapters are either accompanied with glossaries that explain new terminology or timelines that position pioneering scholars and their major discoveries in their historical contexts. The contributing authors outline the history and original context of discovery of symbiosis, symbiogenesis, lateral gene transfer, hybridization or divergence with gene flow and infectious heredity. By applying key insights from the areas of molecular (phylo)genetics, microbiology, virology, ecology, systematics, immunology, epidemiology and computational science, they demonstrate how reticulate evolution impacts su...
IoT Technologies for Health Care
This proceedings constitutes the refereed proceedings of the 8th International Conference on IoT Technologies for Healthcare, HealthyIoT 2021, held in November 2021. Due to COVID-19 pandemic the conference was held virtually. The 17 full papers presented were carefully selected from 40 submissions. The papers are organized in topical sections on security and privacy - software and application security; human-centered computing - ubiquitous and mobile computing; information systems – information retrieval; applied computing - physical sciences and engineering; applied computing – life and medical sciences.
Experimental Evolution
Experimental approaches to evolution provide indisputable evidence of evolution by directly observing the process at work. Experimental evolution deliberately duplicates evolutionary processes—forcing life histories to evolve, producing adaptations to stressful environmental conditions, and generating lineage splitting to create incipient species. This unique volume summarizes studies in experimental evolution, outlining current techniques and applications, and presenting the field’s full range of research—from selection in the laboratory to the manipulation of populations in the wild. It provides work on such key biological problems as the evolution of Darwinian fitness, sexual reproduction, life history, athletic performance, and learning.
OECD Competition Assessment Reviews: Portugal Volume II - Self-Regulated Professions
Against this backdrop, this report examines regulations for 13 self-regulated professions (lawyers, solicitors, notaries, bailiffs, architects, engineers, technical engineers, certified accountants, auditors, economists, customs brokers, nutritionists and pharmacists).
Anthropological Perspectives on Aging
An in-depth and wide-ranging approach to the study of older adults in society Taking a holistic approach to the study of aging, this volume uses biological, archaeological, medical, and cultural perspectives to explore how older adults have functioned in societies around the globe and throughout human history. As the world’s population over 65 years of age continues to increase, this wide-ranging approach fills a growing need for both academics and service professionals in gerontology, geriatrics, and related fields. Case studies from the United States, Tibet, Turkey, China, Nigeria, and Mexico provide examples of the ways age-related changes are influenced by environmental, genetic, socio...
Ecoepigenetics in Clonal and Inbreeding Plants: Transgenerational Adaptation and Environmental Variation
Clonality is widespread in plant species, and clonal plants often have a broad geographic range and long lifespan. Clonality can maintain high fitness in the short term, but vegetative reproduction is commonly considered to preclude adaptation to changing conditions. However, an increasing body of empirical and theoretical evidence suggests that epigenetic modifications such as DNA methylation can provide an alternative to gene-driven evolution through natural selection and allow clonal plants to maintain fitness in the long term. To deepen our understanding of clonal ecology, this collection of research papers and reviews focuses on how epigenetic regulation can encode phenotypic plasticity and contribute to the rapid adaptation of clonal plants to accelerating global and regional environmental changes.
Evolution of Organismal Form: From Regulatory Interactions to Developmental Processes and Biological Patterns
Today's biodiversity is the spectacular product of hundreds of millions of years of evolution. Understanding how this diversity of living organisms appeared is one of the most intriguing and challenging question in biology. Because organismal morphology is established during embryonic development, and because morphological traits diversified from ancestral forms during evolution, it can be inferred that changes in the mechanisms controlling embryonic development are instrumental for morphological evolution. This syllogism lies at the very heart of a new discipline called Evo-Devo which is centered in the identification of the cellular and genetic mechanisms that, through modifications in dev...
