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Frontiers in Parasitology is an Ebook series devoted to publishing the latest and the most important advances in parasitology. Eminent scientists present reviews on the microbiology, cytology, epidemiology, genomics, and molecular biology of microbial parasites and their associated infections. Additionally, the series also gives information about new diagnostic and therapeutic protocols. The Ebook series is essential reading to all scientists involved in studying harmful microbes and their impact on human health.
This book provides a detailed evidence-based overview of the latest developments in how the structure of the human genome is relevant to the health professional. It features comprehensive reviews of genome science including human chromosomal and mitochondrial DNA structure, protein-coding and noncoding genes, and the diverse classes of repeat elements of the human genome. These concepts are then built upon to provide context as to how they functionally relate to differences in phenotypic traits that can be observed in human populations. Guidance is also provided on how this information can be applied by the medical practitioner in day-to-day clinical practice. Human Genome Structure, Function and Clinical Considerations collates the latest developments in genome science and current methods for genome analysis that are relevant for the clinician, researcher and scientist who utilises precision medicine techniques and is an essential resource for any such practitioner.
The maintenance of telomeres—repetitive sequences at the end of chromosome—is essential to health. Dysfunction in telomere maintenance pathways plays a role in aging, cancer, atherosclerosis and other diseases. This has led to telomere maintenance as a prime target for patient therapies. This book describes the advances in telomere research as it applies to human health and especially how lifestyle and dietary factors could modify the telomerase maintenance process. The book examines the mechanisms involved, the primary of which are oxidative stress and the role of sirtuins, and how they can be modified by dietary patterns such as Mediterranean diet.
This special volume of Progress in Molecular Biology and Translational Science focuses on telomeres in health and disease. This volume covers a variety of topics with reviews written by experts in the field. - Contributions from specialists in telomere diseases - Informs and updates on how telomere dysfunction may cause disease in humans
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O Instituto de Geriatria e Gerontologia da Pontifícia Universidade do Rio Grande do Sul (IGG/PUCRS) foi criado em 1o de dezembro de 1975. Vinculado à Pró-Reitoria de Pesquisa e Pós-Graduação, é considerado o berço da Geriatria Acadêmica no Brasil e tem como objetivo principal realizar pesquisas relacionadas ao envelhecimento humano. No ano em que comemora os 45 anos de sua fundação, oferece aos profissionais que lidam com indivíduos em processo de envelhecimento o livro Geriatria e Gerontologia Clínica. Esta publicação, escrita por diversos especialistas, será extremamente útil para todos os profissionais que se pre-ocupam em proporcionar à população um envelhecimento bem-sucedido.