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The cost for bringing new medicine from discovery to market has nearly doubled in the last decade and has now reached $2.6 billion. There is an urgent need to make drug development less time-consuming and less costly. Innovative trial designs/ analyses such as the Bayesian approach are essential to meet this need. This book will be the first to provide comprehensive coverage of Bayesian applications across the span of drug development, from discovery, to clinical trial, to manufacturing with practical examples. This book will have a wide appeal to statisticians, scientists, and physicians working in drug development who are motivated to accelerate and streamline the drug development process,...
Though it defies consensus, between 1900 & 2006 campaigns of nonviolent resistance were more than twice as effective as violent struggles. This study combines statistical analysis with case studies to debunk the myth that violence occurs because of structural & environmental factors & is necessary to achieve certain political goals.
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