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This book analyzes the factors that have sparked pandemics over the past 2000 years, from the Antonine Plague to COVID-19. It is noteworthy that the frequency of pandemics has increased over the past 2000 years. The authors identify three main drivers for the development of pandemics: transportation, human development, and changes in natural ecosystems. It is important to note that with the advent of the industrial age, the length of time it takes for a pandemic to develop has decreased. COVID-19 is certainly not the last pandemic we will face. Therefore, it is of paramount importance to learn from the past 2000 years to help educate general community and public health officials about pandemic risks and help governments prepare for the next pandemic. The book is also very useful in low and middle-income countries where, in the last several decades, viruses with potential for pandemics have originated. It's comprehensiveness and didactic style make this book a valuable read for government health agencies, private organizations, health care professionals and students.
This book consolidates the current knowledge of how short and long-duration spaceflight affects the anatomy and physiology of the central nervous system. It also incorporates the methodology and constraints of studying the central nervous system in space. Chapters detail advances in imaging techniques available to assess intracranial and intraocular pathology as well as translational medicine with an emphasis on brain cancer and neurodegenerative disease in spaceflight. Additionally, the book offers theoretical background information, tested laboratory protocols, and step-by-step methods for reproducible lab experiments to aid neuroscientists and neurobiologists in laboratory testing and experimentation. Spaceflight and the Central Nervous System is the first to comprehensively include all aspects of spaceflight-induced changes in the central nervous system. It is an invaluable resource for basic and clinical laboratory trainees and researchers in aerospace medicine and physiology or for those looking to gain specific knowledge in spaceflight neuroscience.
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Our anatomy and physiology have been completely shaped by Earth's gravity. All body systems function in synergy with this unseen force. Yet, as we journey further and longer into space, our bodies must conform to a new reality, wherein gravity is absent or reduced, cosmic radiation threatens and our social and familial connections become distant. Into Space: A Journey of How Humans Adapt and Live in Microgravity gives an overview of some of the physiological, anatomical and cellular changes that occur in space and their effects on different body systems, such as the cardiovascular and musculoskeletal, and touches on cultural and psychosocial aspects of leaving behind family and the safety of Earth. It further addresses the complexity of manned space flights, showing how interdisciplinary this subject is and discussing the challenges that space physiologists, physicians and scientists must face as humans seek to conquer the final frontier.
Both nutrition deficiency and overnutrition can have a significant effect on the risk of infection. Nutrition, Immunity, and Infection focuses on the influence of diet on the immune system and how altering one’s diet helps prevent and treat infections and chronic diseases. This book reviews basic immunology and discusses changes in immune function throughout the life course. It features comprehensive chapters on obesity and the role of immune cells in adipose tissue; undernutrition and malnutrition; infant immune maturation; pre- and probiotics; mechanisms of immune regulation by various vitamins and minerals; nutrition and the aging immune system; nutrition interactions with environmental...
Basic Anesthesiology Examination Review is a high-yield, streamlined study aid specifically designed for Anesthesiology residents preparing for the American Board of Anesthesiology (ABA) Basic Anesthesiology Exam. Chapters deliver succinct and efficiently communicated summaries of all content listed in the ABA exam outline, plus highlighted key facts, mneomnics, and relevant images and diagrams. Chapters conclude with board-style practice questions and annotated answers, followed by key references and further reading. With this book as a guide, readers will be able to efficiently prepare for the Basic Anesthesiology Examination and master the key facts and concepts that provide the scientific roundation for the practice of Anesthesiology.
The volatile anesthetics continue to be one of the most mysterious yet commonly used class of drugs in medical practice today. A prominent and troublesome side effect of volatile anesthetics is their ability to alter hemodynamics. This arises from two diverse but interrelated phenomena, depression of cardiac contractility and dilation of the vasculature. These effects of volatile anesthetics on cardiac and smooth muscle plus the action of volatile anesthetics on skeletal muscle in the malignant hyperthermic syndrome have led to concern about the interaction of volatile anesthetics (and other anesthetic agents) with calcium metabolism in the muscle cell. Many of the phenomena caused by anesth...