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Genetic Variants as Targets for Immunotherapy of Hematological Tumors
  • Language: en
  • Pages: 139

Genetic Variants as Targets for Immunotherapy of Hematological Tumors

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Allorecognition by Leukocytes of the Adaptive Immune System
  • Language: en
  • Pages: 107

Allorecognition by Leukocytes of the Adaptive Immune System

The term allorecognition refers to the series of mechanisms used by an individual’s immune system to distinguish its own cells and tissues from those of another individual belonging to the same species. During evolution, different cells and molecules of both innate and adaptive immune systems have been selected to recognize and respond to antigens expressed by allogeneic cells, but not autologous cells (alloantigens). This research topic focuses on allorecognition by lymphocytes of the adaptive immune system and its involvement in rejection or tolerance of allogeneic transplants. T and B cells recognizing alloantigens via specific receptors become activated and undergo proliferation and di...

Mechanisms of Tumor Escape from the Immune Response
  • Language: en
  • Pages: 290

Mechanisms of Tumor Escape from the Immune Response

  • Type: Book
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  • Published: 2002-12-12
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  • Publisher: CRC Press

The progressive growth of a malignant tumor is accompanied by a decline in the immune response, through mechanisms that have, until recently, been poorly understood. The new era of biological therapies, including cytokines, adoptive transfer of TIL cells, gene therapy and others, brought forth the need to understand the impact of the tumor on the immune system. Moreover, the inability to achieve in humans the unequivocal success of immunotherapy in murine models suggests the possibility that cancer can impair the development of a therapeutic immune response. Scientific and technological advances in cellular and molecular biology during the last two decades have provided new tools with which ...

Advances In Pediatric Hematopoietic Cell Therapies And Transplantation
  • Language: en
  • Pages: 112

Advances In Pediatric Hematopoietic Cell Therapies And Transplantation

Dr Patrick Hanley, a Topic Editor for this collection, is a co-founder and serves on the board of directors of Mana Therapeutics, a private biotech company focused on cellular therapy for AML. All other Topic Editors declare no competing interests with regards to the Research Topic.

Immunogenicity of Proteins Used as Therapeutics
  • Language: en
  • Pages: 328

Immunogenicity of Proteins Used as Therapeutics

Topic Editor Susan Richards is an employee of Sanofi and owns stock in the corporation. Topic Editor Bernard Maillere declares economic support from pharmaceutical companies (Novartis, Sanofi, and UCB) in the frame of collaborations aiming to evaluate the recognition by human T cells of therapeutic proteins and antibodies.

Cholesterol Metabolism in Health and Disease
  • Language: en
  • Pages: 214

Cholesterol Metabolism in Health and Disease

  • Type: Book
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  • Published: 1985
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  • Publisher: Unknown

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Thrombosis and Haemostasis
  • Language: en
  • Pages: 768

Thrombosis and Haemostasis

  • Type: Book
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  • Published: 1991
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  • Publisher: Unknown

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Kort en krachtig
  • Language: nl

Kort en krachtig

  • Type: Book
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  • Published: Unknown
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  • Publisher: Unknown

None

The Journal of Immunology
  • Language: en
  • Pages: 1218

The Journal of Immunology

  • Type: Book
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  • Published: 2004
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  • Publisher: Unknown

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