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L'Enfant sacrifié
À la fin de ses études supérieures, Laura rejoint sa première affection d’assistante sociale. Le quotidien de la jeune femme est bouleversé : quitter les grands-parents qui l’ont élevée pour bâtir sa carrière s’avère plus difficile que ce qu’elle avait imaginé. En quelques mois, Laura affronte les difficultés de son métier, noue de nouvelles amitiés, et connaît les débuts d’une idylle. Grâce à son obstination, elle exerce le métier de ses rêves. Pourtant, un grand vide occupe son cœur. Que s’est-il vraiment passé lors de l’accident mystérieux qui a coûté la vie à ses parents ? Dans son roman L’Enfant sacrifié, Marielle Spenle nous plonge dans le quotidien turbulent d’une jeune assistante sociale, entre dilemmes, vocation, et secret de famille.
Beyond Galileo
Captain Vaughn returns to space to captain the most advanced ship ever made. He and his crew embark on a routine resupply mission to a colony when they must search for their missing sister ship. They find a lot more than they were prepared for and end up in a continuous struggle to survive. They are on their own in deep space with no hope of any rescue. Their biggest challenges are survival and trying to return to earth.
Feminist Frameworks
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Cancer and Inflammation
Chronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and wound healing. The cells involved in inflammation are detected in a range of common cancers, together with the inflammatory cytokines and members of the chemokine ligand/receptor systems. Neutralization or deletion of the gene for some inflammatory cytokines confers resistance to tumour induction and experimental metastasis. Over-expression of such cytokines in tumour cells may enhance malignant potential. Certain chemokines are likely to subvert antitumour immunity by favouring development of ineffective Type 2 responses. Tumour cells may even uti...
The Most Beautiful Opera Houses in the World
Opera houses--temples to the art of Mozart, Verdi, Tchaikovsky, and more--have been created by some of the most talented architects and designers of their generations, inspiring centuries of veneration from audiences, filled with royalty and commoners alike. In this sumptuous book, photographer Guillaume de Laubier and journalist Antoine Pecqueur explore more than 25 of the world's most beautiful opera houses, from Tokyo to Covent Garden, from Oslo to Chicago, from Milan to New York. The buildings are described in their historical contexts, while stunning photography reveals the theaters' most captivating spaces. In addition to offering sweeping views of ornate auditoriums and facades, the b...
Utopias of the British Enlightenment
A major collection of tracts from the British utopian tradition.
The Proprotein Convertases
Proprotein convertases (PCs) are a family of proteases including PC1, PC2, Furin, PC4, PACE4, PC5, and PC7. These enzymes are involved in the maturation of many precursor proteins involved in the process of tumorigenesis and metastasis. Since their discovery, PCs were suggested as potential targets for anti-cancer therapy, and their activity was found to directly affect tumor cell proliferation, migration invasion, and the malignant phenotypes of tumor cells. Here, we discuss a number of previous and recent findings on the PCs features, their implication in the regulation of multiple cellular functions that impact on the invasive/metastatic potential of cancer cells, and their clinical relev...
