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Drug Resistance in Leishmania Parasites
One of the main problems concerning therapeutic tools for the treatment of parasitic diseases, including leishmaniasis, is that some field parasites are naturally resistant to the classical drugs; additionally, current therapies may select parasites prone to be resistant to the applied drugs. These features are (at least partially) responsible for the disappointing persistence of the disease and resultant deaths worldwide. This book provides a comprehensive view of the pathology of the disease itself, and of parasitic drug resistance, its molecular basis, consequences and possible treatments. Scientists both from academic fields and from the industry involved in biomedical research and drug design, will find in this book a valuable and fundamental guide that conveys the knowledge needed to understand and to improve the success in combating this disease worldwide.
Chemoinformatics
"Low-income populations in developing regions of Africa, Asia and the Americas have been particularly injured by a group of tropical infections denominated neglected diseases. Compared to important illnesses, neglected diseases do not enjoy significant res"
ABC Transporters in Microorganisms
This concise volume describes the latest, up-to-date theory, methodology, and applications of ABC transporters in microorganisms. The topics include the structure, physiology, and evolution of ABC transporters, as well as their special characteristics in specific microorganisms, including bacteria, yeast, trypanosomes, and malaria parasites. In particular, the book describes the most recent research and innovations relative to the role of ABC transporters in the design of strategies to circumvent drug resistance in microorganisms. Each chapter comprises an exhaustive review of the particular topic and provides insights into the future of the field, both from the scientific and clinical perspective. A skillful selection of topics and a panel of acknowledged experts ensure that this concise volume will be of exceptional importance to everyone involved in DNA superfamily research, as well as scientists interested in microbial physiology and multidrug resistance. It is essential reading for anyone involved in this field, and it is a recommended volume for all microbiology laboratories.
Doing December Differently
Explores how people of faith and goodwill might mark the midwinter season and the Christmas festival with integrity and simplicity.
Who's Who Among Hispanic Americans
All areas of the United States have been surveyed to insure balanced national coverage in this work on Hispanic Americans. The work covers individuals from a broad range of professions and occupations, including those involved in medicine, social issues, labour, sports, entertainment, religion, business, law, journalism, science and technology, education, politics and literature. Listees have been selected on the basis of achievement in their fields and/or for considerable civic responsibility.
Drug Resistance in Leishmania Parasites
Drug resistance is a fundamental factor in treatment failure in diseases like leishmaniasis, although additional factors also play a role in this phenomenon. This volume is the second edition of a well-received book that provides a comprehensive update on the pathology of the disease, as well as on the concept of parasitic drug resistance, its molecular basis, consequences and possible treatments. A valuable resource for scientists both from academia and industry involved in biomedical research and drug design, the book provides the knowledge needed to understand leishmaniasis and to contibute to combatting this disease worldwide.
The Danube Basin
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Global Change and Human Mobility
This book demonstrates the benefits of applying a new interdisciplinary approach that combines global change and human mobility. The term "globility" was coined in the year 2000 when the commission with the same name was created by the International Geographical Union with the purpose of theorizing about and asserting the concept of human mobility. First the book offers theoretical reviews of human mobility. Then it proceeds to study patterns of mobility in today's world as it faces new challenges in migration policies (including border controls, management of refugee movements, social initiatives to empower unauthorized immigrants), the integration issue, environmental hazards, and so on. The response to these diverse challenges reveals an increasing fluidity of human mobility and new forms of engagement of people on the move. Readers will obtain a better understanding of current human mobility from a large number of regions and from different thematic perspectives.
