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The Chemistry of Organocopper Compounds
Copper in organic synthesis has seen a tremendous development over the past ten years. This text represents the most comprehensive survey on the use of Copper and Cuprates in organic synthesis. The first time that the Patai Series touches on Copper compounds, it contains contributions by leading experts, and delivers the quality expected from the Patai Series.
Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic
Volume 19, entitled Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic of the series Metal Ions in Life Sciences centers on the role of metal ions in clinical medicine. Metal ions are tightly regulated in human health: while essential to life, they can be toxic as well. Following an introductory chapter briefly discussing several important metal-related drugs and diseases and a chapter about drug development, the focus is fi rst on iron: its essentiality for pathogens and humans as well as its toxicity. Chelation therapy is addressed in the context of thalassemia, its relationship to neurodegenerative diseases and also the risks connected with iron adminis...
On the Nature of Ecological Paradox
This work is a large, powerfully illustrated interdisciplinary natural sciences volume, the first of its kind to examine the critically important nature of ecological paradox, through an abundance of lenses: the biological sciences, taxonomy, archaeology, geopolitical history, comparative ethics, literature, philosophy, the history of science, human geography, population ecology, epistemology, anthropology, demographics, and futurism. The ecological paradox suggests that the human biological–and from an insular perspective, successful–struggle to exist has come at the price of isolating H. sapiens from life-sustaining ecosystem services, and far too much of the biodiversity with which we...
Investigating Life in the Universe
This textbook gives a lively introduction to the search for extraterrestrial life. It is a guidebook to understanding the possibility of life elsewhere, pointing out landmarks and providing background information to facilitate further exploration of those areas of most interest to the reader. We are a planet of winners – winners of a cosmic lottery that has been in play since the universe began approximately 13.7 billion years ago. Our winnings include sentience and an underlying unease that has driven us to contemplate our place in the universe and the possibility of finding kindred spirits in the cosmos spreading out before us. To understand our origins and the possibility of life beyond...
Tellurium Chemistry
Tellurium, a well-known chalcogen, finds potential applications in various fields from chemistry to other branches of science such as nanotechnology and macromolecular science. However, its safety must also be taken into consideration when exploring its industrial applications. This book explores the breadth of tellurium's applications, outlines strategies for industrial use, and describes the safety concerns of this element.
Biomineralization
Biomineralization is a hot topic in the area of materials, and this volume in the Metals Ions in Life Sciences series takes a systematic approach, dealing with all aspects from the fundamentals to applications. Key biological features of biomineralization, such as gene directed growth and the role of enzymes are covered, as are new areas, including copper/zinc in the jaws of invertebrates or magnetic biomaterials that help birds with navigation
Metal Ions in Toxicology
It is an old wisdom that metals are indispensable for life. Indeed, severalof them, like sodium, potassium, and calcium, are easily discovered in livingmatter. However, the role of metals and their impact on life remainedlargely hidden until inorganic chemistry and coordination chemistryexperienced a pronounced revival in the 1950s. The experimental and theoreticaltools created in this period and their application to biochemicalproblems led to the development of the field or discipline now known asBioinorganic Chemistry, Inorganic Biochemistry, or more recently alsooften addressed as Biological Inorganic Chemistry.By 1970 Bioinorganic Chemistry was established and further promoted bythe book...
Environmental Microbiology
Environmental microbiology is the study of microbial processes in the environment, microbial communities and microbial interactions. This includes: - Structure and activities of microbial communities - Microbial interactions and interactions with macroorganisms - Population biology of microorganisms - Microbes and surfaces (adhesion and biofilm formation) - Microbial community genetics and evolutionary processes - (Global) element cycles and biogeochemical processes - Microbial life in extreme and unusual little-explored environments
Organometallics in Environment and Toxicology
Volume 7, devoted to the vital and rapidly expanding research area around metal-carbon bonds (see also MILS-6), focuses on the environment. With more than 2500 references, 35 tables, and nearly 50 illustrations, many of these in color, it is an essential resource for scientists working in the wide range from organometallic chemistry, inorganic biochemistry, environmental toxicology all the way through to physiology and medicine. In 14 stimulating chapters, written by 29 internationally recognized experts, Organometallics in Environment and Toxicology highlights in an authoritative and timely manner environmental cycles of elements involving organometal(loid) compounds as well as the analytical determination of such species. This book examines methane formation involving the nickel coenzyme F430, as well as the organometal(loid) compounds formed by tin, lead, arsenic, antimony, bismuth, selenium, tellurium, and mercury. In addition, it deals with the environmental bioindication, biomonitoring, and bioremediation of organometal(loid)s, and it terminates with methylated metal(loid) species occurring in humans by evaluating assumed and proven health effects caused by these compounds.
The Alkali Metal Ions: Their Role for Life
MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the context of all kinds of biologically relevant ligands are covered, this includes proteins (enzymes) and nucleic acids (G-quadruplexes). Minerals containing sodium (Na+) and potassium (K+) are abundant in the Earth's crust, making Na+ and K+ easily available. In contrast, the alkali elements lithium (Li+), rubidium, and cesium are rare and the radioactive francium occurs only in traces. Since the intra- and extracellular, as well as the compartme...
