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Psychiatric Genomics
Psychiatric Genomics presents and synthesizes available knowledge in the field of psychiatric genomics, offering methodologies to advance new research and aid clinical translation. After providing an introduction to genomics and psychiatry, international experts discuss the genomic basis of schizophrenia, bipolar disorder, depression, personality disorders, anxiety disorders, addictions, eating disorders, and sleep disorders, among other disorders. In addition, recommendations for next steps in clinical implementation and drug discovery are discussed in-depth, with chapters dedicated to pharmacogenomics and antipsychotics, antidepressants and mood stabilizers, adverse drug reactions, impleme...
Bipolar Disorders
Responding to the explosion of research on the pathophysiology and management of bipolar disorder, this completely revised Second Edition spans basic mechanisms, neuroimaging, viral etiology, neurofactors, current treatment implications, and modern theories of the neurobiology of bipolar disorder to stand as the most authoritative reference on this
Pharmacogenetics of Psychotropic Drugs
Pharmacogenetics and pharmacogenomics are areas of significant importance at the interface of molecular genetics and psychopharmacology, with implications for drug development and clinical practice. This 2002 book provides a conceptual framework for understanding and studying the pharmacogenetics of psychotropic drugs, reviews advances in the field, and describes the established findings. Coverage extends to antipsychotics, antidepressants, mood stabilising, cognitive-enhancing and anxiolytic drugs. Chapters also examine the interface of pharmacogenetics with substance dependence and brain imaging, and consider its impact on the biotechnology and pharmaceutical industries. This book defines the young field of pharmacogenetics as it applies to psychotropic drugs, and is therefore of interest to all clinicians and researchers working in this field.
Psyche in the Lab
Commemorating the 25th anniversary of the Canadian Psychiatric Research Foundation, this volume celebrates the creativity and dedication of Canadian scientists who have helped unravel some of the mysteries of the mind over recent years. The authors used criterion-based techniques to select 16 leading scientists for semi-structured interviews, as well as well-known philanthropists, policy-makers, and psychiatric survivors. The fascinating interviews and reports not only show what motivates such outstanding individuals, but also describe what Canada and other countries can do to encourage more and better neuroscience. Those interviewed or reported on include researchers like Martin Alda, Dan Offord, Bruno Cormier, Cheryl Grady, Raymond Lam, Herta Guttman, Zindel Segal, Harvey Chochinov, Remi Quirion, Philip Seeman, Rachel Morehouse, Katherine Hegadoren, Juan Carlos Negrete; as well as Doris Sommer-Rotenberg, Michael Alzamora, Don Tapscott, Ana Lopes, Ross Taylor, Beva Dudiak, Sandra Sharwood, Edward Bronfman, Michael H. Wilson, Earla Dunbar, Joseph Tanenbaum, and Renee Marier.
The Science and Practice of Lithium Therapy
This book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action. The book is divided into two parts, on the science of lithium and the practice of lithium therapy. The former covers aspects such as the properties of the lithium ion, pharmacokinetics and pharmacodynamics, impact on neurotransmission, and gene expression modulation. The section on practice includes discussion of variability in response to lithium, use of lithium in the treatment of bipolar disorders, its value in suicide prevention, administration during pregnancy and in the pediatric age group, and side effects. Lithium is arguably...
Cybersecurity for Decision Makers
This book is aimed at managerial decision makers, practitioners in any field, and the academic community. The chapter authors have integrated theory with evidence-based practice to go beyond merely explaining cybersecurity topics. To accomplish this, the editors drew upon the combined cognitive intelligence of 46 scholars from 11 countries to present the state of the art in cybersecurity. Managers and leaders at all levels in organizations around the globe will find the explanations and suggestions useful for understanding cybersecurity risks as well as formulating strategies to mitigate future problems. Employees will find the examples and caveats both interesting as well as practical for e...
