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Emerging Nanomaterials for Advanced Technologies
  • Language: en
  • Pages: 796

Emerging Nanomaterials for Advanced Technologies

Over the past decade the world has seen the rise of the fascinating and diverse field currently recognized as nanotechnology. This book covers a broad spectrum of topics within nanotechnology, including synthesis techniques, various innovative characterization techniques, growth mechanisms of nanomaterials, the physics and chemistry of nanomaterials, diverse functionalization methods, and the various applications of nanomaterials in biology, therapeutics, energy, food science, and environmental science. It also discusses applications of nanostructured materials, integrative applications such as nano- and micro-electronic sensor devices, as well as agricultural and environmental remediation a...

Cancer
  • Language: en
  • Pages: 452

Cancer

This volume reviews advances in cancer chemotherapy research over the last 10 years. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs. Each chapter covers the drug target and biological rationale, chemotypes, clinical status and future prospects in this rapidly developing area of drug research.

Cyclodextrins
  • Language: en
  • Pages: 334

Cyclodextrins

Authored by two experts working in this important field of research, the timely book covers the latest advances in the synthesis of cyclodextrins, their properties and important industrial applications. To this end, the authors describe covalent and non-covalent assemblies, cyclodextrin inclusion complexes, cyclodextrin polymers, and modified cyclodextrins, resulting in an up-to-date overview of cyclodextrin chemistry. An invaluable reference for organic and polymer chemists in academia as well as those researchers in industry working in polymer, supramolecular and pharmaceutical chemistry, as well as food, textile and cosmetic science.

Green Techniques for Organic Synthesis and Medicinal Chemistry
  • Language: en
  • Pages: 726

Green Techniques for Organic Synthesis and Medicinal Chemistry

An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal C...

The Good Life
  • Language: en
  • Pages: 512

The Good Life

  • Type: Book
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  • Published: 2014-10-09
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  • Publisher: Hachette UK

Everything comes at a price... Hard-hitting and uncompromising, THE GOOD LIFE by the 'undisputed queen of crime writing' (Guardian) and Sunday Times No.1 bestseller Martina Cole is a chilling thriller about power and protection, and what life is really like on the inside. When Cain Moran is sentenced to life in prison, he rules the inside with the same determination as he did the London underworld. He must protect his family, at whatever cost. Jenny Riley has never wanted anyone but Cain, and she will do everything she can to keep their relationship alive. But plenty of people think Cain and Jenny have been living the good life for too long. And they're about to make them pay... For more compelling novels about life on the inside, be sure to read Martina Cole's FACELESS, TWO WOMEN and THE JUMP

Lead-Seeking Approaches
  • Language: en
  • Pages: 224

Lead-Seeking Approaches

High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of compounds that have been preselected for the target of interest. Virtual screening methods such as structure-based or pharmacophore-based searches can complement or replace one of the above approaches. Once hits are identi?ed from one or more of these ...

The History of Cyclodextrins
  • Language: en
  • Pages: 409

The History of Cyclodextrins

This book presents the historical development of Cyclodextrins by scientists who have made outstanding contribution to the field. Cyclodextrins are safe, cage-like molecules that have found major applications in many industrial sectors such as medicine, food, agriculture, environment and chemistry.

MRI of the Temporomandibular Joint
  • Language: en
  • Pages: 238

MRI of the Temporomandibular Joint

This book is the outcome of a fruitful, long-standing cooperation between expert radiologists and clinicians, and explains the most relevant features and technical requirements that are needed to optimally conduct and assess MR examinations for temporomandibular joint (TMJ) pathologies. TMJ conditions are increasingly gaining attention, as the underlying diseases involved can vary considerably and be difficult to diagnose. Similarly, several imaging sub-specialties (e.g. dental radiology, neuroradiology, and musculoskeletal radiology) now find themselves dealing with the temporomandibular joints. The authors provide essential information on TMJ anatomy, dynamics, function and dysfunction. Correlations between clinical aspects and MRI findings are discussed and guidance for the correct interpretation of results is offered. Special findings that are helpful for differential diagnosis (arthritis, osteochondroma, synovial chondromatosis) are also examined. Given its extensive and varied coverage, the book offers a valuable asset for radiologists, dentists, gnathologists, maxillofacial surgeons, orthodontists and other professionals seeking a thorough overview of the subject

Flow Chemistry in Drug Discovery
  • Language: en
  • Pages: 501

Flow Chemistry in Drug Discovery

This book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharma...