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Proton Therapy
Over the past twenty-five years, proton therapy has become more prominent worldwide. It is an important component of clinical radiation therapy for both adult and pediatric clinical care. Due to the inherent ability of protons to spare normal tissue, protons will continue to develop and become increasingly important in radiation oncology. As such, Proton Therapy - Current Status and Future Directions reviews many aspects of proton care including the application of protons in modern clinical trials. It also reviews problems associated with the migration of proton care worldwide and examines the future direction of proton care. This project was created by colleagues at IntechOpen and was caref...
Proton Therapy - Scientific Questions and Future Direction
Proton therapy is rapidly expanding in patient care throughout the world. Once limited to a few centers of care, continued process improvements in the scope and design of proton facilities have now permitted proton centers to develop at an enterprise level in multiple geographic centers. This is important for all aspects of patient care in both adult and pediatric patients. Although initially felt to be limited to a selected number of disease sites, proton therapy, such as stereotactic radiosurgery, can be easily applied to all disease sites. Intensity-modulated proton therapy is now delivered on a routine basis, as proton centers now have tools used by photon systems to deliver care. Coupled with the integration of image guidance, proton centers now can deliver therapy with the ease of photon centers with the distinct advantage of additional sparing of normal tissue. The trajectory of proton care is significant; however, there remains much to be learned about proton care as we review and compare outcomes. This addresses several key issues that will help us further refine proton care in the future.
Oncologic Emergency Medicine
The expanded second edition of this key clinical reference provides the most up-to-date and comprehensive review of oncologic emergencies. It covers the diagnosis and management of the full range of emergencies caused directly by cancer and/or treatment, including chemotoxicity, radiotoxicity and post-surgical complications, as well as transplant-related issues and toxicities of novel antineoplastic agents and the new immunotherapies. The book also shows how the entire spectrum of clinical medicine is brought to bear in the care of cancer patients in the unique setting of the emergency department (ED), from health promotion and prevention, to treatment and palliative care. Recognizing the mu...
Emergency Medicine and Trauma
From prehospital evaluation to management in the emergency department,"Emergency Medicine and Trauma" provides easily accessible information on the evaluation, diagnosis, and management of trauma care. Recognition of the multidisciplinary nature and complexity of trauma care, especially the philosophy of a teamwork approach, must be an integral part of trauma management. To help make logical diagnoses and treatment plans , you will learn: The use of a structured and prioritized approach to critically ill and injured patients according to the clinical need and assessment of acuity level; How to establish resuscitation (management) priorities in a multiply injured patient; How to demonstrate the ability to adopt a holistic (multidisciplinary, biopsychosocial) approach to trauma patients. The role of the emergency department and its staff in major incidents, to understand planning and be prepared for major incidents. This book is designed not only for emergency medical providers but also for medical students.
Trauma and Emergency Surgery
One of the most interesting and challenging fields of surgery is trauma and emergency surgery. The formation of a trauma surgical subspecialty has led to a more organized system of dealing with trauma as well as saving lives. Emergency surgery has been the evolution of this, as an effort to incorporate the knowledge and skills of trauma surgery, intensive care, and emergency general surgery, all in one specialty. This is a collection of chapters describing the nature of damage control surgery, which is one of the key concepts and strategies for managing the most challenging trauma and emergency surgery patients. The authors of this book represent a team of true global experts on the topic. In addition to the knowledge shared, the authors provide their personal clinical experience in a variety of different aspects of damage control surgery.
Advances in Dosimetry and New Trends in Radiopharmaceuticals
Advances in Dosimetry and New Trends in Radiopharmaceuticals is organized into two sections. The first section discusses different dosimetry methods that are used in radiotherapy systems, such as image-guided radiotherapy (IGRT). The second section examines the types and quality of radiochemical applications in nuclear medicine and their radiation dosimetry analysis.
Neuroimaging
In vivo brain neuroimaging with cutting-edge technologies has achieved great success with high spatial and temporal resolutions. Several distinct medical imaging perspectives such as disease neurobiology, multimodal imaging techniques and applications, large-size clinical trials of neuro-oncology, and bioinformatics with illustrative examples and comprehensive summaries could expand our knowledge of neuroimaging mechanism, methodologies, and applications. This book highlights the possibility and achievement of early detection and multiple neuroimaging biomarkers based on various features for pathophysiological probing and therapeutic prevention. It examines the use of neuroimaging techniques such as magnetic resonance imaging (MRI), electroencephalography (EEG), and near-infrared resonance spectroscopy (NIRS) with specific and innovative biomedical applications. It provides thorough reviews, accurate descriptions, and confirmative evidences of many related important research topics together with up-to-date imaging network management.
Essentials of Accident and Emergency Medicine
As physicians, we have a constant passion for improving and maintaining patient's care and safety. The book is divided into three parts focusing on the essentials of general concepts, diagnosis, and management of accident and emergency medicine, as well as an academic approach to teaching in the emergency setting. The chapters selected for this book are written by an excellent group of recognized emergency surgeons and physicians from different countries and cultures facilitating a comprehensive and interesting approach to the problems of emergency treatment. We hope this book will be helpful and used worldwide by medical students, clinicians, and researchers enhancing their knowledge and advancing their objectives by a book that intends to become a reference text for research and practice within accident and emergency medicine.
Translational Research in Cancer
Translational research in oncology benefits from an abundance of knowledge resulting from genome-scale studies concerning the molecular pathways involved in tumorigenesis. Translational oncology represents a bridge between basic research and clinical practice in cancer medicine. The vast majority of cancer cases are due to environmental risk factors. Many of these environmental factors are controllable lifestyle choices. Experimental cancer treatments are studied in clinical trials to compare the proposed treatment to the best existing treatment through translational research. The key features of the book include: 1) New screening for the development of radioprotectors: radioprotection and anti-cancer effect of β-Glucan (Enterococcus faecalis) 2) Translational perspective on hepatocellular carcinoma 3) Brachytherapy for endometrial cancer 4) Discovery of small molecule inhibitors for histone methyltransferases in cancer
Head and Neck Cancer
In recent years, great advances in translational research have led to new paradigms in the treatment of cancers of the head and neck. Written by leading international physicians and investigators, this innovative multi-disciplinary book presents the most up-to-date research and clinical approaches. Coverage is given to progress in a variety of clinical settings, including programs of organ and function preservation, curative treatments, unresectable disease, adjuvant treatments in high-risk patients, and recurrent/metastatic disease. Complementary to the techniques of surgery, radiotherapy, and systemic treatments, the authors present data on epidemiology, molecular pathology, normal tissue complications, rehabilitation, palliative care, and treatment in the elderly. State-of-the-art functional imaging is elucidated; and the latest developments in high precision techniques in irradiation, sequencing of chemo- and radiotherapy, as well as the integration of biomolecular therapies into cytotoxic treatments are explored.
