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Metallothioneins in Normal and Cancer Cells
This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system.
Oral Cancer
Oral cancer is a significant public health challenge globally. Although the oral cavity is easily accessible, early diagnosis remains slow compared to the enhanced detection of cancers of the breast, colon, prostate, and melanoma. As a result, the mortality rate from oral cancer for the past four decades has remained high at over 50% in spite of advances in treatment modalities. This contrasts with considerable decrease in mortality rates for cancers of the breast, colon, prostate, and melanoma during the same period. This book attempts to provide a reference-friendly update on the etiologic/risk factors, current clinical diagnostic tools, management philosophies, molecular biomarkers, and progression indicators of oral cancer.
Fire
The association between our ancestors and fire, somewhere around six to four million years ago, had a tremendous impact on human evolution, transforming our earliest human ancestor, a being communicating without speech but with insight, reason, manual dexterity, highly developed social organization, and the capability of experimenting with this new technology. As it first associated with and then began to tame fire, this extraordinary being began to distance itself from its primate relatives, taking a path that would alter its environment, physiology, and self-image. Based on her extensive research with nonhuman primates, anthropologist Frances Burton details the stages of the conquest of fire and the systems it affected. Her study examines the natural occurrence of fire and describes the effects light has on human physiology. She constructs possible variations of our earliest human ancestor and its way of life, utilizing archaeological and anthropological evidence of the earliest human-controlled fires to explore the profound physical and biological impacts fire had on human evolution.
The Golgi Apparatus and Centriole
This volume takes a closer look how the cell organelles Golgi apparatus (also known as the Golgi complex or Golgi body), and centriole are structurally and functionally intertwined. Initially, it was believed that the role of Golgi complex is limited to the packaging and preparation for secretion of various cellular proteins, while the centriole participates in cell division and cilia formation. However, since their discovery nearly 200 years ago, it became clear that these two organelles are interacting, and that their functions are much more complex and far reaching than previously thought. Recent findings indicate that the Golgi–Centriole relationship may be important for directional pr...
Anticancer Research
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Small Animal Dermatology - E-Book
Designed with busy practitioners and students in mind, Small Animal Dermatology: A Color Atlas and Therapeutic Guide provides concise, thorough coverage of over 250 skin diseases affecting small animals. More than 1,000 high-quality images help to ensure accurate diagnoses, with coverage including clinical features, top differentials, treatment, and prognosis for each disorder. In this edition, author Keith A. Hnilica streamlines content for practical, everyday use in the clinic. The differential diagnosis chapter is updated for added clarity and easier use, and for quick access, chapters now list diseases based upon the frequency of their occurrence in the pet population. - A user-friendly ...
