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Functional Relevance of Tetraspanins in the Immune System
Tetraspanins are small (20-50 kDa) integral membrane proteins with four transmembrane domains that have an intrinsic propensity to associate with other membrane proteins and lipids giving rise to the formation of specific tetraspanin-enriched microdomains (TEMs), also referred to as “The tetraspanin web”. In mammals, the tetraspanin family comprises of 33 different members, with the majority of the members being abundantly expressed in almost all cell types, including leukocytes which are responsible for innate and adaptive immunity as well as in other cells that play pivotal roles in immune responses, such as endothelial or stromal cells. Therefore, through the wide range of specific molecular interactions in which they are engaged, tetraspanins influence many processes of up-most relevance in the development, physiology and pathology of the immune system, including the control of immune cell morphology, signaling, adhesion, migration, invasion, fusion, infections and cancer.
The Case for Marriage
A groundbreaking look at marriage, one of the most basic and universal of all human institutions, which reveals the emotional, physical, economic, and sexual benefits that marriage brings to individuals and society as a whole. The Case for Marriage is a critically important intervention in the national debate about the future of family. Based on the authoritative research of family sociologist Linda J. Waite, journalist Maggie Gallagher, and a number of other scholars, this book’s findings dramatically contradict the anti-marriage myths that have become the common sense of most Americans. Today a broad consensus holds that marriage is a bad deal for women, that divorce is better for childr...
Nanomaterials for 2D and 3D Printing
The first book to paint a complete picture of the challenges of processing functional nanomaterials for printed electronics devices, and additive manufacturing fabrication processes. Following an introduction to printed electronics, the book focuses on various functional nanomaterials available, including conducting, semi-conducting, dielectric, polymeric, ceramic and tailored nanomaterials. Subsequent sections cover the preparation and characterization of such materials along with their formulation and preparation as inkjet inks, as well as a selection of applications. These include printed interconnects, passive and active modules, as well as such high-tech devices as solar cells, transparent electrodes, displays, touch screens, sensors, RFID tags and 3D objects. The book concludes with a look at the future for printed nanomaterials. For all those working in the field of printed electronics, from entrants to specialized researchers, in a number of disciplines ranging from chemistry and materials science to engineering and manufacturing, in both academia and industry.
