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Advances in Electrocardiology 2004
  • Language: en
  • Pages: 892

Advances in Electrocardiology 2004

Electrocardiology has witnessed a century of development since the introduction of Einthoven's Galvanometer. With rapid progress in the scientific, technological and clinical aspects of the field of electrocardiology in recent years, electrocardiology now covers a wide range of topics from molecules as the electrical origin of the heart to diagnostic and therapeutic applications for cardiovascular diseases. This volume presents the latest information and developments in the field, from basic science to clinical electrocardiology. A wide range of topics are covered, including molecular biology, genetics, channelopathy, atrial fibrillation, catheter ablation, modeling of cardiac electrical act...

Myocardial Ischemia and Preconditioning
  • Language: en
  • Pages: 564

Myocardial Ischemia and Preconditioning

Current evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector. Each of these steps in is now its own intense area of investigation. The need to render the heart ischemic for a brief period to invoke the preconditioning response is currently the major factor limiting clinical application of this powerful cardioprotective strategy. Recent research efforts have utilized brief exposures to pharmacological agents, in lieu of a brief preconditioning ischemia, to trigger/mimic the ischemic preconditioning-induced response. The World Heart Congress held in Winnipeg in July 2001 provided a forum for the presentation of new insights into the basic mechanisms of ischemia and reperfusion injury, as well as novel strategies to protect the heart from cell death, ventricular arrhythmias, and contractile dysfunction. Many pioneers in the fields of ischemia-reperfusion injury and preconditioning-induced protection presented there and the chapters in this book represent selected papers from these symposia.

Cellular Function and Metabolism
  • Language: en
  • Pages: 214

Cellular Function and Metabolism

A variety of metabolic processes are known to be intimately involved in the maintenance of cellular structure and function. It has also become clear that metabolic events involved in the synthesis and hydrolysis of ATP as well as for the synthesis of proteins and phospholipids are essential for cellular health. The regulation of cell function is generally achieved through participation of a wide variety of hormones and different signal transduction mechanisms for the activation/deactivation of some specific metabolic processes. In this regard cyclic AMP and calcium seem to play a crucial role. Various hormones are also known to affect the genetic machinery of all the cell; however, the exact...

Clinical Cardiogenetics
  • Language: en
  • Pages: 405

Clinical Cardiogenetics

  • Type: Book
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  • Published: 2016-11-30
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  • Publisher: Springer

Clinical management and signs are the focus of this practical cardiogenetic reference for those who are involved in the care for cardiac patients with a genetic disease. With detailed discussion of the basic science of cardiogenetics in order to assist in the clinical understanding of the topic. The genetic causes of various cardiovascular diseases are explained in a concise clinical way that reinforces the current management doctrine in a practical manner. The authors will cover the principles of molecular genetics in general but also specific to cardiac diseases. They will discuss the etiology, pathogenesis, pathophysiology, clinical presentation, clinical diagnosis, molecular diagnosis an...

Electrical Diseases of the Heart
  • Language: en
  • Pages: 600

Electrical Diseases of the Heart

This book provides a unique contemporary and succinct distillation of the current status of recently delineated electrical diseases of the heart, emphasizing their common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science. The book is divided into seven major parts. Each part consists of chapters (total of 64) dealing with related topics.

Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters
  • Language: en
  • Pages: 586

Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters

Knowledge of cardiac ion channels and transporters has advanced remarkably in the last two decades with the development of patch-clamp and molecular biological techniques. This textbook offers a comprehensive overview of structures and functions of ion channels and transporters in the heart. Readers are first introduced to the molecular biology and electrophysiology of all the important ion channels. After discussing their developmental changes, the pharmacology and pathophysiology of clinically-relevant ion channels are reviewed. Molecular aspects of the cardiac excitation-contraction coupling and intracellular Ca2+ regulation by ion transporters are also described. The book will be useful to electrophysiologists, cardiac physiologists and pharmacologists, and molecular biologists interested in ion channels at all levels. For research specialists, the book will provide a perspective of the field. The book can be used as a reference source for working scientists in the fields of ion channels, biophysics, cardiac electrophysiology, and pharmacology. It is aimed at graduate and medical students, designed for use as a textbook for graduate and medical courses.

Heart Physiology and Pathophysiology
  • Language: en
  • Pages: 1286

Heart Physiology and Pathophysiology

  • Type: Book
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  • Published: 2000-10-09
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  • Publisher: Elsevier

Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage ...

Molecular and Cellular Mechanisms of Cardiovascular Regulation
  • Language: en
  • Pages: 452

Molecular and Cellular Mechanisms of Cardiovascular Regulation

This volume contains selected papers presented at the Sendai International Sympo sium on Molecular and Cellular Mechanisms of Cardiovascular Regulation held from May 10-12, 1995, to honor the contributions ofProfessorNorio Taira, Chairman of the Department of Pharmacology (1972-1995), Tohoku University School of Medicine, Sendai, Japan. The Department of Pharmacology at Sendai has a long tradition of significant contribution to the development of drug therapy for cardiovascular diseases. The late Professor Koroku Hashimoto, the predecessor of Professor Norio Taira, first suggested the mode of action of calcium antagonists and their potential usefulness in therapy of ischemic heart disease an...

AHA Scientific Sessions 2016: Program Information
  • Language: en

AHA Scientific Sessions 2016: Program Information

The American Heart Association’s Scientific Sessions 2016 is bringing big science, big technology, and big networking opportunities to New Orleans, Louisiana this November. This event features five days of the best in science and cardiovascular clinical practice covering all aspects of basic, clinical, population and translational content.

Recent Progress in Electropharmacology of the Heart
  • Language: en
  • Pages: 240

Recent Progress in Electropharmacology of the Heart

  • Type: Book
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  • Published: 1995-12-05
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  • Publisher: CRC Press

This book contains proceedings of the International Satellite Symposium of the 59th Annual Scientific Meeting of the Japanese Circulation Society held in April, 1995 in Nagoya, Japan. The symposium integrates the widespread recent advances on the electropharmacology of the heart from single channels to human patients. Expert researchers in basic physiology, pharmacology, clinical cardiology, and heart surgery discuss their opinions in four areas of cardiac drug and therapy development: molecular morphology and regulation of potassium channels mode of actions and potential usefulness of specific bradycardic agents as well as potassium channel openers cellular and clinical pharmacology of amiodarone and new Class-III antiarrhythmic drugs advantages and disadvantages of newly introduced non-pharmacological therapy of arrhythmias such as implantable cardioverter defibrillators, catheter ablation, and surgery Recent Progress in Electropharmacology of the Heart is a valuable reference for medical students and residents, senior investigators and researchers, and cardiologists who need an up-to-date source on the current drug treatment of arrhythmias and ischemic heart disease.