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Crumbling Genome
A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that are caused, exclusively or primarily, by pre ]existing and new mutations in their genomes,...
Angria
Kanhoji Angre is born to Tukoji Sankhpal, keeper of the Suvarnadurg Fort for Shivaji, emperor of the Marathas. A child of the seas, Kanhoji is as much at home in the turbulent waters of Konkan as in the forts and forests of the Desha mainland. But the enemies of their empire are never too far away. The Mughals are in constant battle with the Marathas on land, while the Siddis and the newly arrived Portuguese threaten to destroy them at sea. There’s also the British East India Company who have arrived as traders and settled on the island of Kulaba, paying taxes to Kanhoji. Kanhoji must rise above conspiracy, deceit, war and family politics to become the Samudratala Shivaji—‘Shivaji of the Seas’. An astounding debut, Angria is the tale of one of history’s most feared naval commanders. Amid the smell of gunpowder and salt, Sohail Rekhy brings to life a momentous era when the war for swaraj was fought on the seas of India and when only one man stood between the firangis and the Desha. This is the chronicle of a hero whose story has been lost to the waves of time.
Johannes Gutenberg and the Shadow of Bi Sheng
Without language, not much else would exist: no writing, no computer – as a matter of fact, no technical or medical progress that make our lives less painful, and easier indeed; but also not some horrors that characterize our world. In fact, language is what defines humans and distinguishes them from other living beings – and is the basis of all other developments. How is it possible that something as complex and fascinating as 'language' has come into being at all? How does language 'work'? And how did it develop? What is common to all languages – and why are there so many? Further questions are how man began to write, and how printing developed – in which languages? Why not in any language? And does this teach us anything for further developments? In trying to answer these and other questions, we experience an exciting history of scientific research.
What's Real about Race?: Untangling Science, Genetics, and Society (A Norton Short)
A paradigm-shifting tour of genetics and identity arguing that race is at once a biological fiction and a social reality. Biologically, race does not exist. Scientists have proven that human DNA is 99.9 percent identical. But we know that racism and its structural impacts shape our health, opportunities, and lives in profound ways. What is the true relationship between genetics and race? And how should we talk about identity in science and medicine? In What’s Real About Race?, sociologist Rina Bliss illuminates the truth about one of the most misunderstood, controversial concepts in our society and reveals why we cannot confuse race with genetic difference. Blending energizing prose with t...
Nanobiotechnology
This book covers topics related to drug delivery, biomaterials, drug design, formulation development, nanoscience, and nanotechnology. It describes the fundamental concepts in nanotechnology and their different applications in biotechnology to solve engineering challenges and generate new areas of technological development. Nanobiotechnology: Applications of Nanomaterials in Biotechnology, Medicine, and Healthcare covers vast application areas that include medical science, material science, pharmaceutical science, and environmental science. Section 1 presents recent research updates on the different nanomaterials, which are promising in different medical and biotechnological applications. Ap...
Herbal Pharmacopeia
This book comprehensively explores the intersection between traditional herbal medicine and cutting-edge nanotechnology. The chapters introduce modern techniques used in herbal extraction and analysis. The principles of drug discovery from plants are discussed, with a focus on the identification and development of bioactive compounds that have therapeutic potential. It discusses the pharmacological properties, biotechnological approaches in drug development, and challenges in the formulation and standardization of herbal medicines. Emerging trends and applications of nanotechnology in herbal pharmacotherapy, such as nanoparticle synthesis, enhanced bioavailability using nanocarriers, safety ...
Human Diversity
All people are equal but, as Human Diversity explores, all groups of people are not the same -- a fascinating investigation of the genetics and neuroscience of human differences. The thesis of Human Diversity is that advances in genetics and neuroscience are overthrowing an intellectual orthodoxy that has ruled the social sciences for decades. The core of the orthodoxy consists of three dogmas: - Gender is a social construct. - Race is a social construct. - Class is a function of privilege. The problem is that all three dogmas are half-truths. They have stifled progress in understanding the rich texture that biology adds to our understanding of the social, political, and economic worlds we live in. It is not a story to be feared. "There are no monsters in the closet," Murray writes, "no dread doors we must fear opening." But it is a story that needs telling. Human Diversity does so without sensationalism, drawing on the most authoritative scientific findings, celebrating both our many differences and our common humanity.
Dilip Kumar
An authentic, heartfelt and compelling narrative – straight from the horse’s mouth – that reveals for the first time numerous unknown aspects of the life and times of one of the greatest legends of all time who stands out as a symbol of secular India. Dilip Kumar (born as Yousuf Khan), who began as a diffident novice in Hindi cinema in the early 1940s, went on to attain the pinnacle of stardom within a short time. He came up with spellbinding performances in one hit film after another – in his almost six-decade-long career – on the basis of his innovative capability, determination, hard work and never-say-die attitude. In this unique volume, Dilip Kumar traces his journey right fro...
