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This book summarizes scientific advances in our understanding of the interrelationship between obsessive-compulsive symptoms and schizophrenia and reflects on the implications for future research directions. In addition, guidelines are provided on practical assessment, diagnosis and treatment interventions, covering both pharmacotherapy and psychotherapy. The book acknowledges the need for a perspective that recognizes heterogeneous subgroups and diverse neurobiological explanations; accordingly, multidimensional research-based conceptual frameworks are provided that incorporate recent epidemiological, neurocognitive, neurogenetic and pharmacodynamic findings. Obsessive-Compulsive Symptoms in Schizophrenia has been written by an international team of experts who offer insights gained through their extensive experience. It will be an invaluable guide to this frequent and clinically important comorbidity and will be particularly useful for mental health practitioners.
In recent years, mental illnesses have become recognized as a huge emotional and financial burden to the individual, their relatives and society at large. Stress-related and mood disorders as well as psychoactive substance abuse are among the disorders associated with most disability in high income countries. Suicide, which is often attributed to some underlying mental disorders, is a leading cause of death among teenagers and young adults. At the same time, mental disorders pose some of the toughest challenges in neuroscience research. There are many different categories of mental disorder as defined and classified by the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) and th...
Although monotherapy is generally recommended as the treatment of choice, treatment resistance of patients with psychosis, cognitive, mood and anxiety disorders represents a significant clinical problem. In this context, augmentation and combination strategies are commonly employed to address this problem. Although multiple medication use common in psychiatric practice, reasons, efficacy and safety for polypharmacy, and augmentative strategies have remained unclear. It remains unclear if there is an evidence base to support polypharmacy. Furthermore, excessive and inappropriate use of psychotropic medications has been recognized as a public health problem. This volume is the first comprehensive, clinically oriented, reference on the multiple medication use to treat psychotic, cognitive, mood and anxiety disorders.
Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people glob...
This three-volume set, LNAI 11670, LNAI 11671, and LNAI 11672 constitutes the thoroughly refereed proceedings of the 16th Pacific Rim Conference on Artificial Intelligence, PRICAI 2019, held in Cuvu, Yanuca Island, Fiji, in August 2019. The 111 full papers and 13 short papers presented in these volumes were carefully reviewed and selected from 265 submissions. PRICAI covers a wide range of topics such as AI theories, technologies and their applications in the areas of social and economic importance for countries in the Pacific Rim.
Although monotherapy is generally recommended as the treatment of choice, treatment resistance of patients with psychosis, cognitive, mood and anxiety disorders represents a significant clinical problem. In this context, augmentation and combination strategies are commonly employed to address this problem. Although multiple medication use common in psychiatric practice, reasons, efficacy and safety for polypharmacy, and augmentative strategies have remained unclear. It remains unclear if there is an evidence base to support polypharmacy. Furthermore, excessive and inappropriate use of psychotropic medications has been recognized as a public health problem. This volume set is the first comprehensive, clinically oriented, reference on the multiple medication use to treat psychotic, cognitive, mood and anxiety disorders.
A philosopher who has experienced psychosis argues that recovery requires regaining agency and autonomy within a therapeutic relationship based on mutual trust. In Mental Patient, philosopher Abigail Gosselin uses her personal experiences with psychosis and the process of recovery to explore often overlooked psychiatric ethics. For many people who struggle with psychosis, she argues, psychosis impairs agency and autonomy. She shows how clinicians can help psychiatric patients regain agency and autonomy through a positive therapeutic relationship characterized by mutual trust. Patients, she says, need to take an active role in regaining their agency and autonomy—specifically, by giving test...
This book provides a new compilation of information that link changes in the basic structure of synapses and brain diseases. The book shows that specific secreted proteins, and short peptide mimicking the function of neural cell adhesion molecules can significantly enhance the formation of synapses in the brain. It describes recent advances in research that lay necessary scientific groundwork to develop pharmacological treatments.